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GCM1 产品

(Glial Cells Missing Homolog 1 (GCM1))

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This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008].

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Featured GCM1 Categories

GCM1 抗体

High quality antibodies with extensive validation data.

GCM1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our GCM1 Products

Bailey, Alahari, Tagliaferro, Post, Caniggia: "Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis." in: Cell death & disease, Vol. 8, Issue 2, pp. e2590, (2017) (PubMed).

Zhang, Muralimanoharan, Wortman, Mendelson: "Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia." in: Proceedings of the National Academy of Sciences of the United States of America, (2016) (PubMed).

Moretto Zita, Soncin, Natale, Pizzo, Parast: "Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation." in: The Journal of biological chemistry, Vol. 290, Issue 50, pp. 30152-62, (2015) (PubMed).

Sivasubramaniyam, Garcia, Tagliaferro, Melland-Smith, Chauvin, Post, Todros, Caniggia: "Where polarity meets fusion: role of Par6 in trophoblast differentiation during placental development and preeclampsia." in: Endocrinology, Vol. 154, Issue 3, pp. 1296-309, (2013) (PubMed).

Kumar, Luo, Tudela, Alexander, Mendelson: "The c-Myc-regulated microRNA-17~92 (miR-17~92) and miR-106a~363 clusters target hCYP19A1 and hGCM1 to inhibit human trophoblast differentiation." in: Molecular and cellular biology, Vol. 33, Issue 9, pp. 1782-96, (2013) (PubMed).

Drewlo, Czikk, Baczyk, Lye, Kingdom: "Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi." in: Human reproduction (Oxford, England), Vol. 26, Issue 5, pp. 1025-34, (2011) (PubMed).

Baczyk, Drewlo, Proctor, Dunk, Lye, Kingdom: "Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast." in: Cell death and differentiation, Vol. 16, Issue 5, pp. 719-27, (2009) (PubMed).

Synonyms and alternative names related to GCM1

glial cells missing homolog 1 (GCM1), glial cells missing homolog 1 (Drosophila) (Gcm1), glial cells missing homolog 1 (Gcm1), GCM, GCM-1, Gcm-rs2, GCM1, Gcm1-rs1, GCMA, GCMa, Gcma, glide, hGCMa

Protein level used designations for GCM1

  • glial cells missing homolog 1 (Drosophila)
  • chorion-specific transcription factor GCMa
  • glial cells missing-like protein 1
  • glial cells missing homolog a
  • chorion-specific transcription factor GCMa-like
  • GCM motif protein 1
  • Gcm 1
  • Gcm a
  • glial cell deficient
  • mGCM1
  • mGCMa
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