GAD65 蛋白
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GAD65 Protein (AA 1-585) (GST tag) | 人 | 小麦胚 |
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| GAD65 蛋白 | 小鼠 | Baculovirus infected Insect Cells |
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| GAD65 Protein (His-GST) | 小鼠 | Baculovirus infected Insect Cells |
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| GAD65 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| GAD65 Protein (AA 1-585) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| GAD65 Protein (AA 1-585) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| GAD65 Protein (AA 188-374) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GAD65 Protein (AA 65-105) (His tag,GST tag) | 人 | 大肠杆菌（E. Coli） |
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| GAD65 Protein (AA 188-374) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| GAD65 Protein (AA 1-585, full length) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GAD65 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| GAD65 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| GAD65 Protein (AA 1-494) (His tag) | Arabidopsis thaliana | 酵母菌 |
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| GAD65 Protein (AA 152-496) (His tag) | 人 | Bacteria |
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| GAD65 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| GAD65 蛋白 | 人, 大鼠, 小鼠 | 大肠杆菌（E. Coli） |
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| GAD65 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
2 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Arabidopsis thaliana
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our GAD65 蛋白
: "Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet ?-cells." in: Cellular immunology, Vol. 273, Issue 2, pp. 115-23, (2012) (PubMed).
: "Thymus-specific deletion of insulin induces autoimmune diabetes." in: The EMBO journal, Vol. 28, Issue 18, pp. 2812-24, (2009) (PubMed).
: "Thymus-specific deletion of insulin induces autoimmune diabetes." in: The EMBO journal, Vol. 28, Issue 18, pp. 2812-24, (2009) (PubMed).
Aliases for GAD65 蛋白
glutamate decarboxylase 2 (GAD2) 蛋白glutamate decarboxylase 2 (PTRG_06148) 蛋白
glutamate decarboxylase 2 (LOC9324534) 蛋白
glutamate decarboxylase 2 (Gad2) 蛋白
glutamate decarboxylase 1 (GAD1) 蛋白
glutamate decarboxylase 2 (gad2) 蛋白
glutamic acid decarboxylase 2 (Gad2) 蛋白
6330404F12Rik 蛋白
F12P19.12 蛋白
F12P19_12 蛋白
GAD(65) 蛋白
Gad-2 蛋白
GAD65 蛋白
gad65 蛋白
GLUTAMATE DECARBOXYLASE 2 蛋白
glutamate decarboxylase 2 蛋白
zgc:112198 蛋白
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