GAD65 蛋白
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Quick Overview for GAD65 蛋白 (ABIN7849739)
抗原
See all GAD65 (GAD2) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Glutamic Acid Decarboxylase65,GAD65Protein
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Tris-HCl, pH 7.4±0.2 with 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
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- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
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别名
- GAD65
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背景
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Synonyms: 65 kDa glutamic acid decarboxylase, DCE 2, DCE2, GAD 2, GAD 65, GAD-2, GAD-65, GAD 65, GAD2, Glutamate Decarboxylase 2 (pancreatic islets and brain 65 kDa), Glutamate Decarboxylase 2, Glutamate Decarboxylase 65, Glutamate decarboxylase 65 kDa isoform, Glutamic Acid Decarboxylase 2, Glutamic Acid Decarboxylase 65.
Description: Recombinant human Glutamic Acid Decarboxylase 65 protein with his tag at N-terminal with molecular weight of 80 kDa.
Background: Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. In mammals, GAD exists in two isoforms encoded by two different genes - GAD1 and GAD2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD65 and GAD67 synthesize GABA at different locations in the cell, at different developmental times, and for functionally different purposes. GAD67 is spread evenly throughout the cell while GAD65 is localized to nerve terminals. Gad67 in Drd1a-expressing neurons plays a key role in the development of LID and they support the hypothesis that altered GABAergic neurotransmission in the direct pathway is involved in dyskinesia.
抗原
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