GAB2 抗体
(GRB2-Associated Binding Protein 2 (GAB2))
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GAB2 抗体 (pTyr643) (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| GAB2 抗体 (pSer159) (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| GAB2 抗体 (pSer623) (Alexa Fluor 594) | 人, 小鼠 | 兔 Polyclonal |
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| GAB2 抗体 (pTyr452) (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| GAB2 抗体 (pTyr643) (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| GAB2 抗体 (pTyr643) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| GAB2 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| GAB2 抗体 (AA 273-484) | 人, 小鼠 | 兔 Polyclonal |
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| GAB2 抗体 (pTyr452) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| GAB2 抗体 (Tyr643) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 488
- 抗原表位
- pTyr643
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 594
- 抗原表位
- pSer159
Primary Antibody
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 594
- 抗原表位
- pSer623
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 594
- 抗原表位
- pTyr452
Primary Antibody
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Alexa Fluor 594
- 抗原表位
- pTyr643
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pTyr643
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 273-484
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr452
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Tyr643
Latest Publications for our GAB2 抗体
: "K48-Linked Ubiquitination Contributes to Nicotine-Augmented Bone Marrow-Derived Dendritic-Cell-Mediated Adaptive Immunity." in: Vaccines, Vol. 9, Issue 3, (2021) (PubMed).
: "PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation." in: Journal of immunology research, Vol. 2018, pp. 5070573, (2018) (PubMed).
: "Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model." in: Synapse (New York, N.Y.), Vol. 68, Issue 4, pp. 168-77, (2014) (PubMed).
: "In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 3, pp. 1102-7, (2014) (PubMed).
: "A role for the scaffolding adapter GAB2 in breast cancer." in: Nature medicine, Vol. 12, Issue 1, pp. 114-21, (2006) (PubMed).
: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).
: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, (2001) (PubMed).
: "PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-κB Inactivation." in: Journal of immunology research, Vol. 2018, pp. 5070573, (2018) (PubMed).
: "Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model." in: Synapse (New York, N.Y.), Vol. 68, Issue 4, pp. 168-77, (2014) (PubMed).
: "In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 3, pp. 1102-7, (2014) (PubMed).
: "A role for the scaffolding adapter GAB2 in breast cancer." in: Nature medicine, Vol. 12, Issue 1, pp. 114-21, (2006) (PubMed).
: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).
: "Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 45175-83, (2001) (PubMed).
Aliases for GAB2 抗体
GRB2 associated binding protein 2 (GAB2) 抗体GRB2 associated binding protein 2 (gab2) 抗体
GRB2-associated binding protein 2 (Gab2) 抗体
growth factor receptor bound protein 2-associated protein 2 (Gab2) 抗体
AI463667 抗体
D130058I17Rik 抗体
GAB2 抗体
p97 抗体
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