GAB2 抗体 (pTyr452)
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Quick Overview for GAB2 抗体 (pTyr452) (ABIN8121816)
抗原
See all GAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr452
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原理
- Gab 2 (phospho Tyr452) Antibody
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特异性
- Phospho-Gab 2 (Y452) Polyclonal Antibody detects endogenous levels of Gab 2 protein only when phosphorylated at Y452.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized phospho-peptide around the phosphorylation site of human Gab 2 (phospho Tyr452)
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亚型
- IgG
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anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 332-476) antibody
GAB2 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1F6D9 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pSer159) antibodyGAB2 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (pTyr452) antibodyGAB2 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 273-484) antibodyGAB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 3-30), (N-Term) antibodyGAB2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21209 unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (Ser159) antibodyGAB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 162-504) antibodyGAB2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 601-676) antibodyGAB2 适用: 人 WB, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (C-Term) antibodyGAB2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 2 (GAB2) (AA 357-607) antibodyGAB2 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
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别名
- Gab 2
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背景
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Synonyms: GAB2, KIAA0571, GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp100
Background: GRB2 associated binding protein 2(GAB2) Homo sapiens This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors.The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009],
Gene Name: GAB2
Protein Name: GRB2-associated-binding protein 2
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基因ID
- 9846
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UniProt
- Q9UQC2
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
抗原
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