FZR1 抗体
(Fizzy/cell Division Cycle 20 Related 1 (FZR1))
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FZR1 抗体 (AA 1-493) | 人 | 小鼠 Monoclonal |
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| FZR1 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 1-494) | 人 | 小鼠 Monoclonal |
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| FZR1 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| FZR1 抗体 (AA 1-101) | 人 | 小鼠 Monoclonal |
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| FZR1 抗体 (AA 1-493) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 35-84) | 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat, 猴, 小鸡, Hamster, 非洲爪蟾 | 兔 Polyclonal |
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| FZR1 抗体 (N-Term) | 人, 小鼠, 大鼠, Bat, 猴 | 兔 Polyclonal |
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| FZR1 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| FZR1 抗体 (AA 1-496) | 人 | 小鼠 Monoclonal |
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| FZR1 抗体 (AA 141-240) (Cy3) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (Cy7) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (FITC) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (Cy5) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (HRP) | 人 | 兔 Polyclonal |
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| FZR1 抗体 (AA 141-240) (Biotin) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- PLA (Proximity Ligation Assay: 有验证图片)
- ISt (Immunostaining: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4C4
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 1-493
Primary Antibody
- WB (Western Blotting: 有验证图片)
1 reference - 适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4C4
- 标记
- unconjugated
- 抗体亚型
- IgG2a kappa
- 抗原表位
- AA 1-494
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3E12
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 1-101
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-493
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB39496
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 53-81, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1621CT637-76-67
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-496
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 141-240
Latest Publications for our FZR1 抗体
: "APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion." in: Cellular and molecular neurobiology, Vol. 39, Issue 1, pp. 123-135, (2019) (PubMed).
: "Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 19, pp. 9423-9432, (2019) (PubMed).
: "Inhibition of neddylation causes meiotic arrest in mouse oocyte." in: Cell cycle (Georgetown, Tex.), Vol. 18, Issue 11, pp. 1254-1267, (2019) (PubMed).
: "G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 7, pp. 2925-2936, (2017) (PubMed).
: "Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival." in: Scientific reports, Vol. 6, pp. 31158, (2016) (PubMed).
: "Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).
: "Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Issue 19, pp. 9423-9432, (2019) (PubMed).
: "Inhibition of neddylation causes meiotic arrest in mouse oocyte." in: Cell cycle (Georgetown, Tex.), Vol. 18, Issue 11, pp. 1254-1267, (2019) (PubMed).
: "G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, Issue 7, pp. 2925-2936, (2017) (PubMed).
: "Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival." in: Scientific reports, Vol. 6, pp. 31158, (2016) (PubMed).
: "Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway." in: Nature communications, Vol. 5, pp. 3480, (2014) (PubMed).
Aliases for FZR1 抗体
fizzy and cell division cycle 20 related 1 (Fzr1) 抗体fizzy/cell division cycle 20 related 1 (CDH1-C) 抗体
fizzy and cell division cycle 20 related 1 (FZR1) 抗体
fizzy-related protein homolog (LOC100027495) 抗体
fizzy-related protein homolog (LOC100179951) 抗体
fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1) 抗体
fizzy/cell division cycle 20 related 1a (fzr1a) 抗体
AW108046 抗体
CDC20C 抗体
CDH1 抗体
Cdh1 抗体
CDH1-C 抗体
FYR 抗体
Fyr 抗体
FZR 抗体
fzr1 抗体
FZR2 抗体
HCDH 抗体
HCDH1 抗体
zgc:55450 抗体
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