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- 抗原 See all FZR1 抗体
- FZR1 (Fizzy/cell Division Cycle 20 Related 1 (FZR1))
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抗原表位
- AA 1-493
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Fizzy-related protein homolog protein (1-493AA)
- 亚型
- IgG
- Top Product
- Discover our top product FZR1 Primary Antibody
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anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-493) antibody
FZR1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (N-Term) antibodyFZR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 141-240) antibodyFZR1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-101) antibodyFZR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-494) antibodyFZR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 224-493) antibodyFZR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-496) antibodyFZR1 适用: 人 WB 宿主: 小鼠 Monoclonal 1621CT637-76-67 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (N-Term) antibodyFZR1 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) antibodyFZR1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 35-84) antibodyFZR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat, 猴, 小鸡, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FZR1 (Fizzy/cell Division Cycle 20 Related 1 (FZR1))
- 别名
- FZR1 (FZR1 产品)
- 别名
- CDH1-C antibody, FYR antibody, FZR antibody, CDH1 antibody, fzr1 antibody, CDC20C antibody, FZR2 antibody, HCDH antibody, HCDH1 antibody, AW108046 antibody, Cdh1 antibody, Fyr antibody, zgc:55450 antibody, fizzy and cell division cycle 20 related 1 antibody, fizzy/cell division cycle 20 related 1 antibody, fizzy-related protein homolog antibody, fizzy/cell division cycle 20 related 1 (Drosophila) antibody, fizzy/cell division cycle 20 related 1a antibody, Fzr1 antibody, CDH1-C antibody, FZR1 antibody, LOC100027495 antibody, LOC100179951 antibody, fzr1a antibody
- 背景
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Background: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
Aliases: CDC20 like 1b antibody, CDC20 like protein 1 antibody, CDC20-like protein 1 antibody, CDC20C antibody, CDH1 antibody, Cdh1/Hct1 homolog antibody, Fizzy related protein 1 antibody, Fizzy related protein antibody, Fizzy related protein homolog antibody, Fizzy-related protein homolog antibody, Fizzy/cell division cycle 20 related 1 antibody, FYR antibody, FZR 1 antibody, FZR 2 antibody, Fzr antibody, FZR_HUMAN antibody, Fzr1 antibody, Fzr1 protein antibody, FZR2 antibody, HCDH 1 antibody, HCDH antibody, hCDH1 antibody, KIAA1242 antibody
- UniProt
- Q9UM11
- 途径
- DNA Replication, Synthesis of DNA
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