FUS 蛋白
(Fused in Sarcoma (FUS))
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
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10 results
FUS
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
ELISA, WB
1 image
FUS
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
5 references
FUS
宿主: Human respiratory syncytial virus A
宿主: 酵母菌
Recombinant
> 90 %
SDS
1 image
FUS
宿主: Human respiratory syncytial virus B
宿主: 酵母菌
Recombinant
> 90 %
SDS
1 image
FUS
宿主: Canine Distemper Virus (CDV)
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
FUS
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
95 %
ELISA
1 image
Latest Publications for our FUS 蛋白
: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).
: "Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways." in: Acta neuropathologica, Vol. 132, Issue 2, pp. 175-96, (2016) (PubMed).
: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).
: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).
Aliases for FUS 蛋白
FUS RNA binding protein (FUS) 蛋白fused in sarcoma (Fus) 蛋白
FUS RNA binding protein (Fus) 蛋白
fused in sarcoma (FUS) 蛋白
ALS6 蛋白
D430004D17Rik 蛋白
D930039C12Rik 蛋白
ETM4 蛋白
FUS/TLS 蛋白
FUS1 蛋白
Fus1 蛋白
HNRNPP2 蛋白
POMP75 蛋白
TLS 蛋白
Tls 蛋白
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