This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008].
Ackema, Prescianotto-Baschong, Hench, Wang, Chia, Mergentaler, Bard, Frank, Spang: "Sar1, a Novel Regulator of ER-Mitochondrial Contact Sites." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154280, (2016) (PubMed).
Edgar: "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12." in: BMC genomics, Vol. 4, Issue 1, pp. 18, (2003) (PubMed).
Aliases for PREB 抗体
prolactin regulatory element binding (PREB) 抗体 prolactin regulatory element binding (Preb) 抗体 C85705 抗体 SEC12 抗体