ELAC2 抗体
(ElaC Homolog 2 (ELAC2))
The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Latest Publications for our ELAC2 抗体
: "Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy. ..." in: Oncotarget, Vol. 10, Issue 48, pp. 4973-4986, (2019) (PubMed).Aliases for ELAC2 抗体
elaC ribonuclease Z 2 (ELAC2) 抗体elaC ribonuclease Z 2 (Elac2) 抗体
1110017O07Rik 抗体
D11Wsu80e 抗体
ELC2 抗体
Hpc2 抗体
HPC2 抗体
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