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ELAC2 产品

(ElaC Homolog 2 (ELAC2))

Categories

The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Featured ELAC2 Categories

ELAC2 抗体

High quality antibodies with extensive validation data.

ELAC2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ELAC2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7263113
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN528451
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN6140108
Quantity 100 μL
Datasheet Datasheet

Recommended ELAC2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229915
Quantity 96 tests
Datasheet Datasheet

Recommended ELAC2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352662
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352660
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3124449
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ELAC2 Products

Schroeder, Navid-Hill, Meiners, Hube-Magg, Kluth, Makrypidi-Fraune, Simon, Büscheck, Luebke, Goebel, Lang, Weidemann, Neubauer, Hinsch, Jacobsen, Lebok, Michl, Pehrke, Huland, Graefen, Schlomm et al.: "Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy. ..." in: Oncotarget, Vol. 10, Issue 48, pp. 4973-4986, (2019) (PubMed).

Synonyms and alternative names related to ELAC2

elaC ribonuclease Z 2 (ELAC2), elaC ribonuclease Z 2 (Elac2), 1110017O07Rik, D11Wsu80e, ELC2, Hpc2, HPC2

Protein level used designations for ELAC2

  • RNase Z 2
  • elaC homolog protein 2
  • ribonuclease Z 2
  • tRNA 3 endonuclease 2
  • tRNase Z 2
  • tRNase Z(L)
  • zinc phosphodiesterase ELAC protein 2
  • elaC homolog 2
  • heredity prostate cancer protein 2
  • putative prostate cancer susceptibility protein HPC2/ELAC2
  • tRNase Z (long form)
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