EIF4G1 产品
(Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
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The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010].
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Featured EIF4G1 Categories
Recommended EIF4G1 抗体
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ABIN515213
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100 μg
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ABIN7263569
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Recommended EIF4G1 ELISA试剂盒
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Recommended EIF4G1 蛋白
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ABIN7122847
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ABIN1352616
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Latest Publications for our EIF4G1 Products
: "Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia." in: American journal of physiology. Endocrinology and metabolism, Vol. 311, Issue 4, pp. E791-E801, (2016) (PubMed).: "DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3764-75, (2015) (PubMed).
: "Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA." in: Molecular and cellular biology, Vol. 34, Issue 3, pp. 439-51, (2014) (PubMed).
: "Dynamic regulation of the translation initiation helicase complex by mitogenic signal transduction to eukaryotic translation initiation factor 4G." in: Molecular and cellular biology, Vol. 33, Issue 5, pp. 937-46, (2013) (PubMed).
: "Anabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E674-86, (2012) (PubMed).
: "A cellular response linking eIF4AI activity to eIF4AII transcription." in: RNA (New York, N.Y.), Vol. 18, Issue 7, pp. 1373-84, (2012) (PubMed).
: "Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 3, pp. 1046-51, (2011) (PubMed).
: "Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2947-59, (2011) (PubMed).
: "Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs." in: The Journal of nutrition, Vol. 141, Issue 12, pp. 2152-8, (2011) (PubMed).
: "Dysregulation of mTOR signaling in fragile X syndrome." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 2, pp. 694-702, (2010) (PubMed).
Synonyms and alternative names related to EIF4G1
eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), eukaryotic translation initiation factor 4G (eIF4G), eukaryotic translation initiation factor 4 gamma, 1a (eif4g1a), eukaryotic translation initiation factor 4 gamma 1 (LOC704923), eukaryotic translation initiation factor 4 gamma, 1 S homeolog (eif4g1.S), eukaryotic translation initiation factor 4G (EIF4G), eukaryotic initiation factor (EIF4G), eukaryotic translation initiation factor 4 gamma (eIF4g), eukaryotic translation initiation factor 4 gamma (Eif4g), eukaryotic translation initiation factor 4 gamma, 1 (Eif4g1), eukaryotic translation initiation factor 4, gamma 1 (Eif4g1), CG10811, CUCUMOVIRUS MULTIPLICATION 2, CUM2, DDBDRAFT_0217646, DDBDRAFT_0217647, DDBDRAFT_0234257, DDB_0217646, DDB_0217647, DDB_0234257, deIF4G, Dmel\\CG10811, E030015G23Rik, eIF-4G, EIF-4G1, EIF4F, EIF4G, Eif4G, eIF4g, eif4g, EIF4G1, EIF4GI, eIF4GI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, eukaryotic translation initiation factor 4G, NV18824, p200, P220, p220, PARK18, wu:fb50a05, wu:fc60b06Protein level used designations for EIF4G1
- eukaryotic translation initiation factor 4 gamma 1
- CG10811-PA
- CG10811-PB
- CG10811-PC
- Eukaryotic-initiation-factor-4G
- eIF-4G
- eIF4G-PA
- eIF4G-PB
- eIF4G-PC
- eukaryotic initiation factor 4G
- translation initiation factor
- translation initiation factor eIF4G
- eukaryotic translation initiation factor 4 gamma, 1
- fb50a05
- eukaryotic initiation factor
- eukaryotic translation initiation factor 4 gamma
- eukaryotic translation initiation factor 4 gamma 1-like
- EIF4-gamma
- eIF-4-gamma 1
- eucaryotic translation initiation factor 4G
- eIF-4G 1
- eIF-4G1
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