ELAC2 抗体 (C-Term)
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北京 101111
Quick Overview for ELAC2 抗体 (C-Term) (ABIN2776757)
抗原
See all ELAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ELAC2 Antibody - C-terminal region
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序列
- ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT
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预测反应
- Dog: 100%, Human: 100%, Mouse: 83%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against ELAC2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ELAC2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41346-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ELAC2 (ElaC Homolog 2 (ELAC2))
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别名
- ELAC2
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背景
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Background Information: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: elaC homolog 2 (E. coli)
Alternative Symbols: ELC2, HPC2, COXPD17
Protein Name: Zinc phosphodiesterase ELAC protein 2
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分子量
- 55kDa
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基因ID
- 60528
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UniProt
- Q9BQ52
抗原
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