ELAC2 抗体 (AA 161-210)
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Quick Overview for ELAC2 抗体 (AA 161-210) (ABIN1534089)
抗原
See all ELAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-210
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原理
- RNase Z2 Antibody
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特异性
- RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ELAC2 (ElaC Homolog 2 (ELAC2))
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别名
- ELAC2
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背景
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Synonyms: ELAC2; HPC2; Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2
Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Gene Name: ELAC2
Protein Name: Zinc phosphodiesterase ELAC protein 2
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分子量
- 92 kDa
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基因ID
- 60528
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OMIM
- 176807
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UniProt
- Q9BQ52
抗原
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