anti-小鼠 PMS2 抗体 for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PMS2 Antibody (supplied by: Log in to see )

抗原
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) 抗体
  • HNPCC4
  • PMS2CL
  • PMSL2
  • AW555130
  • Pmsl2
  • PMS1 homolog 2, mismatch repair system component
  • PMS1 homolog2, mismatch repair system component
  • mismatch repair endonuclease PMS2
  • PMS2
  • Pms2
  • LOC463257
  • LOC107984056
抗原表位
AA 623-639
10
7
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
适用
人, 小鼠
125
41
19
2
2
2
2
1
1
1
1
1
1
1
1
宿主
小鼠
72
53
1
克隆类型
单克隆
标记
This PMS2 antibody is un-conjugated
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
98
55
53
34
28
19
12
9
3
2
2
1
Supplier
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产品编号 ABIN400707
$ 495.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN1723117 IHC (p) WB Mouse IgG1 AA 623-639 Log in to see 163C1251 0
1 ABIN127133 IHC (p) IP WB Rabbit Log in to see Polyclonal 0
-2.0025787 ABIN252510 CyTOF FACS IHC IHC (p) WB Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346504 CyTOF FACS IHC IHC (p) WB Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346507 FACS IHC IHC (p) WB DyLight 650 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346519 FACS IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346508 FACS IHC IHC (p) WB DyLight 680 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346506 IHC IHC (p) WB Biotin Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346510 FACS IHC IHC (p) WB DyLight 755 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346513 FACS IHC IHC (p) WB DyLight 550 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346509 FACS IHC IHC (p) WB DyLight 488 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346515 FACS IHC IHC (p) WB DyLight 405 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346517 FACS IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346518 FACS IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346520 FACS IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4346514 FACS IHC IHC (p) WB DyLight 350 Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4995527 FACS IHC IHC (p) FITC Mouse IgG1 Log in to see 163C1251 0
-12.75825 ABIN4239041 IHC IHC (p) WB HRP Mouse IgG1 Log in to see 163C1251 0

General

抗原 PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) 抗体
抗原表位 AA 623-639
(10), (7), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
适用 人, 小鼠
(125), (41), (19), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
宿主 小鼠
(72), (53), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This PMS2 antibody is un-conjugated
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(98), (55), (53), (34), (28), (19), (12), (9), (3), (2), (2), (1)
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PMS2抗体详情

PMS2目标详情 使用细节 贮存及处理 图像
特异性 Recognizes Postmeiotic Segregation Increased 2 (PMS2).
交叉反应 (详细) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
产品特性 Synonyms: PMSL2, PMS-2, Mismatch repair endonuclease PMS2, PMS1 protein homolog 2, DNAmismatch repair protein PMS2
纯化方法 Protein G Chromatography.
免疫原 Synthetic peptide (KLH conjugated) corresponding to amino acids 623-639 of HumanPMS2. AA Sequence: SSLAKRIKQLHHEAQQS
克隆位点 163C1251
亚型 IgG1
Plasmids, Primers & others

PMS2目标详情

PMS2抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 PMS2 (PMS2 Antibody 摘要)
背景 Mismatch DNA repair in bacteria is carried out by the MutL, MutH, and MutS proteins. The MutS protein initially bunds to mismatched DNA. This is followed by binding of the MutH endonuclease and MutL to form a complex that carries out excision repair. The hMSH2 gene specifies a MutS homologue and hMLH1, hPMS1, and hPMS2 encode MutL homologs. Mutations in these genes are associated with hereditary nonpolyposis colon cancer (HNPCC), one of the most common hereditary diseases in man. As with the bacterial system, HNPCC is characterized by frequent microsatellite mutations that arise by somatic mutation due to a replication error (RER+) phenotype. Both hPMS1 and hPMS2 are mutated in the germline of HNPCC patients. Although the exact function of MutL and its homologs has yet to be determined, it is known that a complex of PMS2 and MLH1 (MutLa) from HeLa cells can complement a deficiency of MLH1 in hypermutable H6 colorectal tumor cells.Synonyms: DNA mismatch repair protein PMS2, Mismatch repair endonuclease PMS2, PMS1 protein homolog 2, PMSL2
基因ID 5395
UniProt P54278
途径 DNA Damage Repair, Production of Molecular Mediator of Immune Response

使用细节

PMS2抗体详情 PMS2目标详情 贮存及处理 图像 回页首
应用备注 Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL. In IHC with FFPE tissues this antibody shows staining of Mucin in Colon in addition to theexpected signal.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

PMS2抗体详情 PMS2目标详情 使用细节 图像 回页首
浓度 0.5 mg/mL
缓冲液 PBS containing 0.02 % Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Shelf life: one year from despatch.
有效期 12 months

图像

PMS2抗体详情 PMS2目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Immunohistochemistry (IHC) image for anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 623-639) antibody (ABIN400707) anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (AA 623-639) antibody