anti-人 PMS2 抗体 for Western Blotting

Recommended PMS2 Antibody (supplied by: Log in to see )

抗原
PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) 抗体
  • HNPCC4
  • PMS2CL
  • PMSL2
  • AW555130
  • Pmsl2
  • PMS1 homolog 2, mismatch repair system component
  • PMS1 homolog2, mismatch repair system component
  • mismatch repair endonuclease PMS2
  • PMS2
  • Pms2
  • LOC463257
  • LOC107984056
抗原表位
Middle Region
10
8
5
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 兔, 大鼠, Yeast (Saccharomyces cerevisiae)
123
42
18
2
2
1
1
1
1
1
1
宿主

69
53
1
克隆类型
多克隆
标记
This PMS2 antibody is un-conjugated
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
95
54
53
35
26
19
11
9
3
2
2
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

产品编号 ABIN2786522
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1703398 ABIN4880958 ELISA FACS ICC WB Mouse IgG1 AA 748-851 Log in to see 1E9D11 0
3.1703398 ABIN1534484 ELISA WB Rabbit IgG AA 461-510 Log in to see Polyclonal 2
3.1703398 ABIN4346521 IF IHC IHC (p) WB Mouse IgG2b Log in to see 2G5 1
3.1703398 ABIN3186513 ELISA IF IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
3.1703398 ABIN252510 CyTOF FACS IHC IHC (p) WB Mouse IgG1 Log in to see 163C1251 0
3.1703398 ABIN5951374 FACS ICC IF IHC IHC (p) IP WB Rabbit IgG Log in to see SY08-09 0
3.1703398 ABIN2668908 WB Mouse IgG AA 623-639 Log in to see 163C1251 0
3.1703398 ABIN2682504 WB Rabbit IgG C-Term Log in to see Polyclonal 0
3.1703398 ABIN5960584 ELISA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
3.1703398 ABIN518994 IF WB Mouse AA 1-862, full length Log in to see Polyclonal 0
3.1703398 ABIN5693181 ELISA WB Rabbit AA 656-767 Log in to see Polyclonal 0
3.1703398 ABIN2970156 IF/ICC WB Rabbit IgG Log in to see Polyclonal 0
3.1703398 ABIN5078899 ICC IF WB Rabbit IgG Log in to see Polyclonal 0
3.1703398 ABIN6258635 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 0
3.1703398 ABIN129513 IP ELISA WB Mouse IgG Log in to see 349-29-5-2 0
3.1703398 ABIN5585870 IHC (p) WB Mouse IgG1 Log in to see 163C1251 0
3.1703398 ABIN2564595 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
3.1703398 ABIN5585871 IF IHC WB Rat Log in to see Polyclonal 0
3.1703398 ABIN518995 WB Rabbit AA 1-862, full length Log in to see Polyclonal 0
3.1703398 ABIN5914770 WB Rabbit Log in to see Polyclonal 0

General

抗原 PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) 抗体
抗原表位 Middle Region
(10), (8), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 兔, 大鼠, Yeast (Saccharomyces cerevisiae)
(123), (42), (18), (2), (2), (1), (1), (1), (1), (1), (1)
宿主
(69), (53), (1)
克隆类型
多克隆
标记 This PMS2 antibody is un-conjugated
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(95), (54), (53), (35), (26), (19), (11), (9), (3), (2), (2), (1)
Pubmed 找到1个引用
Supplier Log in to see

PMS2抗体详情

PMS2目标详情 使用细节 贮存及处理 References for anti-PMS2 antibody (ABIN2786522) 图像
Blocking Peptide Blocking peptide for this product available: ABIN981896
序列 INKKVVPLDF SMSSLAKRIK QLHHEAQQSE GEQNYRKFRA KICPGENQAA
预测反应 Cow: 85%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Rabbit: 92%, Rat: 92%, Yeast: 91%
产品特性 This is a rabbit polyclonal antibody against PMS2. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the middle region of human PMS2
Plasmids, Primers & others

PMS2目标详情

PMS2抗体详情 使用细节 贮存及处理 References for anti-PMS2 antibody (ABIN2786522) 图像 回页首
抗原
别名 PMS2 (PMS2 Antibody 摘要)
背景 PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Alias Symbols: HNPCC4, PMS2CL, PMSL2
Protein Interaction Partner: UBC, MLH1, PCNA, PMS2P1, NSF, MSH2, LMNA, MSH6, SPRTN, BRIP1, FAN1, CLSPN, TOPBP1, PSD2, MMS19, ATAD3A, NSUN2, UBR5, COPG2, PSD3, COPG1, RUVBL2, EXO1, AIFM1, RUVBL1, XPO1, SMARCA4, RFC2, PSMD5, PSMC6, PSMC3, PSMC2, PSMC1, PRKDC, PPP2CA, PIK3C2A, MSH3, MCM
Protein Size: 862
分子量 96 kDa
基因ID 5395
NCBI登录号 NM_000535, NP_000526
UniProt P54278
途径 DNA Damage Repair, Production of Molecular Mediator of Immune Response

使用细节

PMS2抗体详情 PMS2目标详情 贮存及处理 References for anti-PMS2 antibody (ABIN2786522) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 862 AA

限制 仅限研究用

贮存及处理

PMS2抗体详情 PMS2目标详情 使用细节 References for anti-PMS2 antibody (ABIN2786522) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PMS2 antibody (ABIN2786522)

PMS2抗体详情 PMS2目标详情 使用细节 贮存及处理 图像 回页首
背景

Jackson, Holter, Pollett, Clendenning, Chou, Senter, Ramphal, Gallinger, Boycott: "Café-au-lait macules and pediatric malignancy caused by biallelic mutations in the DNA mismatch repair (MMR) gene PMS2." in: Pediatric blood & cancer, Vol. 50, Issue 6, pp. 1268-70, 2008

图像

PMS2抗体详情 PMS2目标详情 使用细节 贮存及处理 References for anti-PMS2 antibody (ABIN2786522) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2) (Middle Region) antibody (ABIN2786522) WB Suggested Anti-PMS2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...