DNMT3A 蛋白
(DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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custom-made
DNMT3A
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
DNMT3A
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Latest Publications for our DNMT3A 蛋白
: "DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro." in: FEBS letters, Vol. 590, Issue 17, pp. 2870-83, (2016) (PubMed).
Aliases for DNMT3A 蛋白
DNA methyltransferase 3 alpha (DNMT3A) 蛋白DNA methyltransferase 3A (Dnmt3a) 蛋白
DNA methyltransferase 3 alpha (Dnmt3a) 蛋白
DNA methyltransferase 3 alpha (dnmt3a) 蛋白
DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab) 蛋白
DNMT3A 蛋白
dnmt3a1 蛋白
DNMT3A2 蛋白
dnmt6 蛋白
M.HsaIIIA 蛋白
MmuIIIA 蛋白
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