DNMT3B 蛋白
(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011].
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9 results
custom-made
DNMT3B
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
DNMT3B
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
DNMT3B
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
SDS, WB, Imm, PC
custom-made
DNMT3B
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Latest Publications for our DNMT3B 蛋白
: "DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro." in: FEBS letters, Vol. 590, Issue 17, pp. 2870-83, (2016) (PubMed).
Aliases for DNMT3B 蛋白
DNA methyltransferase 3 beta (DNMT3B) 蛋白DNA methyltransferase 3 beta (Dnmt3b) 蛋白
DNA methyltransferase 3 beta (dnmt3b) 蛋白
DNA methyltransferase 3B (Dnmt3b) 蛋白
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba) 蛋白
cb91 蛋白
DNMT3B 蛋白
dnmt3bl 蛋白
dnmt7 蛋白
ICF 蛋白
ICF1 蛋白
LOC100218113 蛋白
M.HsaIIIB 蛋白
MmuIIIB 蛋白
sb:cb91 蛋白
wu:fb16h07 蛋白
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