DNMT3A 产品
(DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
Categories
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured DNMT3A Categories
DNMT3A 抗体
High quality antibodies with extensive validation data.
DNMT3A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
DNMT3A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DNMT3A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
- (7)
Cat. No.
ABIN3022834
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (10)
- (5)
Cat. No.
ABIN387881
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN669336
Quantity
100 μL
Datasheet
Datasheet
Recommended DNMT3A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962647
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955416
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1884515
Quantity
96 tests
Datasheet
Datasheet
Recommended DNMT3A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (2)
Cat. No.
ABIN2719617
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122679
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351868
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our DNMT3A Products
: "Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency." in: Cell stem cell, Vol. 24, Issue 1, pp. 123-137.e8, (2019) (PubMed).: "Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. ..." in: Nature genetics, Vol. 51, Issue 1, pp. 96-105, (2019) (PubMed).
: "Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally." in: Diabetes, Vol. 68, Issue 2, pp. 337-348, (2019) (PubMed).
: "The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells." in: Molecular carcinogenesis, (2018) (PubMed).
: "Identification of dynamic undifferentiated cell states within the male germline." in: Nature communications, Vol. 9, Issue 1, pp. 2819, (2018) (PubMed).
: "Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle." in: Reproduction, fertility, and development, Vol. 29, Issue 9, pp. 1729-1738, (2018) (PubMed).
: "DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 11, pp. 1048-1061, (2018) (PubMed).
: "MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6262-6274, (2018) (PubMed).
: "Intragenic DNA methylation prevents spurious transcription initiation." in: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).
: "Epigenetic determinants of space radiation-induced cognitive dysfunction." in: Scientific reports, Vol. 7, pp. 42885, (2017) (PubMed).
Synonyms and alternative names related to DNMT3A
DNA methyltransferase 3 alpha (DNMT3A), DNA methyltransferase 3A (Dnmt3a), DNA methyltransferase 3 alpha (Dnmt3a), DNA methyltransferase 3 alpha (dnmt3a), DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab), DNMT3A, dnmt3a1, DNMT3A2, dnmt6, M.HsaIIIA, MmuIIIAProtein level used designations for DNMT3A
- DNA (cytosine-5)-methyltransferase 3A
- DNA cytosine methyltransferase 3 alpha
- DNA (cytosine-5-)-methyltransferase 3 alpha
- DNA MTase HsaIIIA
- DNA cytosine methyltransferase 3A2
- DNA methyltransferase 3A
- DNA methyl transferase alpha
- DNA-methyltransferase 3a
- DNA MTase MmuIIIA
- DNA methyltransferase MmuIIIA
- LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3A
- DNA (cytosine-5-)-methyltransferase 6
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