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DNM2 产品

(Dynamin 2 (DNM2))
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010].

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Featured DNM2 Categories

DNM2 抗体

High quality antibodies with extensive validation data.

DNM2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DNM2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DNM2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7433204
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
Cat. No. ABIN5611153
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (3)
Cat. No. ABIN7127459
Quantity 100 μL
Datasheet Datasheet

Recommended DNM2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966433
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955474
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1130880
Quantity 96 tests
Datasheet Datasheet

Recommended DNM2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351857
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351859
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3092229
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DNM2 Products

Engevik, Kaji, Postema, Faust, Meyer, Williams, Fitz, Tyska, Wilson, Goldenring: "Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes." in: The Journal of cell biology, Vol. 218, Issue 11, pp. 3647-3662, (2019) (PubMed).

Postema, Grega-Larson, Meenderink, Tyska: "PACSIN2-dependent apical endocytosis regulates the morphology of epithelial microvilli." in: Molecular biology of the cell, Vol. 30, Issue 19, pp. 2515-2526, (2019) (PubMed).

Romani, Papi, Ignesti, Soccolini, Hsu, Gargiulo, Spisni, Cavaliere: "Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 389, Issue 11, pp. 1171-1182, (2016) (PubMed).

Chou, Sem, Wright, Sudhaharan, Ahmed: "Dynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics." in: The Journal of biological chemistry, Vol. 289, Issue 35, pp. 24383-96, (2014) (PubMed).

Sloan, Kuhl, Mesplède, Münch, Donahue, Wainberg: "Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis." in: Journal of virology, (2013) (PubMed).

Jeon, Leibiger, Moede, Walter, Faul, Maiguel, Villarreal, Guzman, Berggren, Mundel, Ricordi, Merscher-Gomez, Fornoni: "Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells." in: The Journal of biological chemistry, Vol. 287, Issue 34, pp. 28932-42, (2012) (PubMed).

Cheng, Shih, Huang, Chi, Wu, Liu: "Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules." in: Journal of virology, Vol. 86, Issue 24, pp. 13653-61, (2012) (PubMed).

Huang, Wang, Chi, Wang, Wang, Lin, Liu et al.: "Cell entry of avian reovirus follows a caveolin-1-mediated and dynamin-2-dependent endocytic pathway that requires activation of p38 mitogen-activated protein kinase (MAPK) and Src signaling pathways ..." in: The Journal of biological chemistry, Vol. 286, Issue 35, pp. 30780-94, (2011) (PubMed).

Min, Leung, Tomas, Watson, Gaisano, Halban, Pessin, Hou: "Dynamin is functionally coupled to insulin granule exocytosis." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33530-6, (2007) (PubMed).

Quan, Robinson: "Rapid purification of native dynamin I and colorimetric GTPase assay." in: Methods in enzymology, Vol. 404, pp. 556-69, (2006) (PubMed).

Synonyms and alternative names related to DNM2

dynamin 2 (DNM2), dynamin 2 (dnm2), dynamin 2 L homeolog (dnm2.L), dynamin 2 (Dnm2), dynamin 2a (dnm2a), dynamin 2-like (DNM2L), CMT2M, cmtdi1, CMTDI1, cmtdib, CMTDIB, DI-CMTB, dnm2, DYIIAAB, dyn2, DYN2, Dyn2, dynamin-2, dynII, DYNII, LCCS5, Udnm, zgc:114072

Protein level used designations for DNM2

  • dynamin-2
  • dynamin 2
  • dynamin-2-like
  • dynamin II
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