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DISC1 抗体

(Disrupted in Schizophrenia 1 (DISC1))
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1\;11)(q42.1\;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

88 results

DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 750 Recombinant Antibody
产品编号 ABIN7774446
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 680 Recombinant Antibody
产品编号 ABIN7774445
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 647 Recombinant Antibody
产品编号 ABIN7774444
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 594 Recombinant Antibody
产品编号 ABIN7774443
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 555 Recombinant Antibody
产品编号 ABIN7774442
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 488 Recombinant Antibody
产品编号 ABIN7774441
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Alexa Fluor 405 Recombinant Antibody
产品编号 ABIN7774440
 
DISC1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IF, FACS 宿主: 兔 Monoclonal Biotin Recombinant Antibody
产品编号 ABIN7774447
 
DISC1 适用: 人 ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN6084505
 
DISC1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6812188
 
DISC1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6844314
 
DISC1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6884567
 
DISC1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 680
产品编号 ABIN6900630
 
DISC1 适用: 人 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN6852441
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN6884568
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN6812189
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN6828252
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN6852442
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6868505
 
DISC1 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6844315
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunoprecipitation (IP)
    • Immunofluorescence (IF)
    • Flow Cytometry (FACS)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Chimpanzee
  • 图像
  • 仅无防腐剂
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 584CT4-2-1
    • 1D4B
    • 22D79
    • R03-7F5
  • 抗原表位
    • AA 761-832
    • AA 701-728
    • C-Term
    • N-Term
    • AA 99-325
    • Internal Region
    • AA 101-260
    • AA 400-500
    • AA 461-477
    • AA 700-728
    • AA 730-750
    • AA 1-200
    • AA 101-200
    • AA 102-261
    • AA 151-330
    • AA 151-340
    • AA 23-85
    • AA 350-400
    • AA 700-800
    • AA 74-91
    • Center
    • Long Isoform
    • Middle Region
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • APC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Alexa Fluor 350
    • Alexa Fluor 405
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • PE
  • 抗体亚型
    • IgG
    • IgM
    • Ig Fraction
    • IgG1
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Acris
    • FabGennix
    • Abcepta
    • Boster Bio
    • Cloud-Clone
    • Covalab
    • Abbexa
    • Angio-Proteomie
    • Wuhan Fine biotech

Latest Publications for our DISC1 抗体

El-Hassar, Simen, Duque, Patel, Kaczmarek, Arnsten, Yeckel: "Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels." in: Biological psychiatry, Vol. 76, Issue 6, pp. 476-85, (2014) (PubMed).

Burdick, Kamiya, Hodgkinson, Lencz, DeRosse, Ishizuka, Elashvili, Arai, Goldman, Sawa, Malhotra: "Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding." in: Human molecular genetics, Vol. 17, Issue 16, pp. 2462-73, (2008) (PubMed).

Taya, Shinoda, Tsuboi, Asaki, Nagai, Hikita, Kuroda, Kuroda, Shimizu, Hirotsune, Iwamatsu, Kaibuchi: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).

Duan, Chang, Ge, Faulkner, Kim, Kitabatake, Liu, Yang, Jordan, Ma, Liu, Ganesan, Cheng, Ming, Lu, Song: "Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain." in: Cell, Vol. 130, Issue 6, pp. 1146-58, (2007) (PubMed).

Hayashi, Portaro, Bastos, Guerreiro, Oliveira, Gorrão, Tambourgi, SantAnna, Whiting, Camargo, Konno, Brandon, Camargo: "Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 10, pp. 3828-33, (2005) (PubMed).

Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, (2005) (PubMed).

Brandon, Handford, Schurov, Rain, Pelling, Duran-Jimeniz, Camargo, Oliver, Beher, Shearman, Whiting: "Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders." in: Molecular and cellular neurosciences, Vol. 25, Issue 1, pp. 42-55, (2004) (PubMed).

Hodgkinson, Goldman, Jaeger, Persaud, Kane, Lipsky, Malhotra: "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder." in: American journal of human genetics, Vol. 75, Issue 5, pp. 862-72, (2004) (PubMed).

Taylor, Devon, Millar, Porteous: "Evolutionary constraints on the Disrupted in Schizophrenia locus." in: Genomics, Vol. 81, Issue 1, pp. 67-77, (2003) (PubMed).

Morris, Kandpal, Ma, Austin: "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation." in: Human molecular genetics, Vol. 12, Issue 13, pp. 1591-608, (2003) (PubMed).

Aliases for DISC1 抗体

disrupted in schizophrenia 1 (disc1) 抗体
disrupted in schizophrenia 1 (DISC1) 抗体
disrupted in schizophrenia 1 protein (LOC100580606) 抗体
disrupted in schizophrenia 1 (Disc1) 抗体
C1orf136 抗体
DISC1 抗体
SCZD9 抗体
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