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DISC1 抗体

(Disrupted in Schizophrenia 1 (DISC1))
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1\;11)(q42.1\;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

83 results

DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN894051
 
DISC1 适用: 人 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN668550
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN668548
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN668547
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN668546
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN668545
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN668544
 
DISC1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN894054
 
DISC1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7150095
 
DISC1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7150094
 
DISC1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7150093
 
DISC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7638031
 
DISC1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7638030
 
DISC1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7094727
 
DISC1 适用: 小鼠 IHC Polyclonal unconjugated
产品编号 ABIN966000
 
DISC1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965999
 
DISC1 适用: 小鼠 IHC Polyclonal unconjugated
产品编号 ABIN965997
 
DISC1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965996
 
DISC1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990780
 
DISC1 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990781
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Chimpanzee
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 584CT4-2-1
    • 1D4B
    • 22D79
    • R03-7F5
  • 抗原表位
    • AA 761-832
    • AA 701-728
    • AA 99-325
    • C-Term
    • N-Term
    • Internal Region
    • AA 101-260
    • AA 102-261
    • AA 151-330
    • AA 151-340
    • AA 400-500
    • AA 461-477
    • AA 700-728
    • AA 730-750
    • AA 1-200
    • AA 101-200
    • AA 23-85
    • AA 350-400
    • AA 700-800
    • AA 74-91
    • Center
    • Long Isoform
    • Middle Region
  • 标记
    • 非结合性
    • FITC
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • APC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • PE
  • 抗体亚型
    • IgG
    • IgM
    • Ig Fraction
    • IgG1
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • USBio
    • Acris
    • FabGennix
    • Abcepta
    • Boster Bio
    • Cloud-Clone
    • Covalab
    • Abbexa
    • Angio-Proteomie
    • Wuhan Fine biotech

Latest Publications for our DISC1 抗体

El-Hassar, Simen, Duque, Patel, Kaczmarek, Arnsten, Yeckel: "Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels." in: Biological psychiatry, Vol. 76, Issue 6, pp. 476-85, (2014) (PubMed).

Burdick, Kamiya, Hodgkinson, Lencz, DeRosse, Ishizuka, Elashvili, Arai, Goldman, Sawa, Malhotra: "Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding." in: Human molecular genetics, Vol. 17, Issue 16, pp. 2462-73, (2008) (PubMed).

Taya, Shinoda, Tsuboi, Asaki, Nagai, Hikita, Kuroda, Kuroda, Shimizu, Hirotsune, Iwamatsu, Kaibuchi: "DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 1, pp. 15-26, (2007) (PubMed).

Duan, Chang, Ge, Faulkner, Kim, Kitabatake, Liu, Yang, Jordan, Ma, Liu, Ganesan, Cheng, Ming, Lu, Song: "Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain." in: Cell, Vol. 130, Issue 6, pp. 1146-58, (2007) (PubMed).

Hayashi, Portaro, Bastos, Guerreiro, Oliveira, Gorrão, Tambourgi, SantAnna, Whiting, Camargo, Konno, Brandon, Camargo: "Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 10, pp. 3828-33, (2005) (PubMed).

Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, (2005) (PubMed).

Brandon, Handford, Schurov, Rain, Pelling, Duran-Jimeniz, Camargo, Oliver, Beher, Shearman, Whiting: "Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders." in: Molecular and cellular neurosciences, Vol. 25, Issue 1, pp. 42-55, (2004) (PubMed).

Hodgkinson, Goldman, Jaeger, Persaud, Kane, Lipsky, Malhotra: "Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder." in: American journal of human genetics, Vol. 75, Issue 5, pp. 862-72, (2004) (PubMed).

Taylor, Devon, Millar, Porteous: "Evolutionary constraints on the Disrupted in Schizophrenia locus." in: Genomics, Vol. 81, Issue 1, pp. 67-77, (2003) (PubMed).

Morris, Kandpal, Ma, Austin: "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation." in: Human molecular genetics, Vol. 12, Issue 13, pp. 1591-608, (2003) (PubMed).

Aliases for DISC1 抗体

disrupted in schizophrenia 1 (disc1) 抗体
disrupted in schizophrenia 1 (DISC1) 抗体
disrupted in schizophrenia 1 protein (LOC100580606) 抗体
disrupted in schizophrenia 1 (Disc1) 抗体
C1orf136 抗体
DISC1 抗体
SCZD9 抗体
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