DIO2 抗体
(Deiodinase, Iodothyronine, Type II (DIO2))
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| DIO2 抗体 (N-Term) | 大鼠 | 兔 Polyclonal |
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|
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| DIO2 抗体 | 大鼠 | 小鼠 Monoclonal |
|
|
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| DIO2 抗体 (AA 165-191) | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 165-191
Latest Publications for our DIO2 抗体
: "Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice." in: The Science of the total environment, Vol. 668, pp. 310-317, (2019) (PubMed).
: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." in: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).
: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." in: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).
: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).
: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." in: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).
: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." in: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).
: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." in: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).
: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." in: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).
: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).
: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." in: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).
: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." in: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).
Aliases for DIO2 抗体
iodothyronine deiodinase 2 (DIO2) 抗体deiodinase, iodothyronine, type II (Dio2) 抗体
iodothyronine deiodinase 2 (dio2) 抗体
deiodinase, iodothyronine, type II (dio2) 抗体
deiodinase, iodothyronine, type 2 L homeolog (dio2.L) 抗体
deiodinase, iodothyronine, type 2 (dio2) 抗体
iodothyronine deiodinase 2 (Dio2) 抗体
type II iodothyronine deiodinase (LOC100861220) 抗体
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