CXCR2 抗体
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
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110 results
CXCR2
适用: 小鼠
WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our CXCR2 抗体
: "Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment." in: Journal of immunology research, Vol. 2018, pp. 7283703, (2019) (PubMed).: "Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration." in: Nature communications, Vol. 8, pp. 15584, (2017) (PubMed).
: "NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo." in: Oncology reports, Vol. 36, Issue 2, pp. 918-28, (2017) (PubMed).
: "Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 124, (2016) (PubMed).
: "Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2807-15, (2016) (PubMed).
: "B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration." in: Scientific reports, Vol. 6, pp. 31284, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "TNF-α augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma." in: Journal of cellular and molecular medicine, Vol. 20, Issue 11, pp. 2020-2028, (2016) (PubMed).
: "Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. ..." in: Cancer discovery, Vol. 6, Issue 1, pp. 80-95, (2016) (PubMed).
Aliases for CXCR2 抗体
C-X-C motif chemokine receptor 2 (Cxcr2) 抗体C-X-C motif chemokine receptor 2 (CXCR2) 抗体
chemokine (C-X-C motif) receptor 2 (Cxcr2) 抗体
CD128 抗体
CD182 抗体
CDw128 抗体
CDw128b 抗体
CMKAR2 抗体
Cmkar2 抗体
CXC-R2 抗体
CXCR-2 抗体
Gpcr16 抗体
IL-8rb 抗体
IL-8Rh 抗体
IL8R2 抗体
IL8RA 抗体
IL8RB 抗体
Il8rb 抗体
mIL-8RH 抗体
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