CXCR2 抗体 (Middle Region)
(5 references)-
- 抗原 See all CXCR2 抗体
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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抗原表位
- AA 196-212, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 2(CXCR2) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- CYEDMGNNTA NWRMLLR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 2(CXCR2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: chemokine(C-X-C motif) receptor 2
Protein Name: C-X-C chemokine receptor type 2(CXC-R2/CXCR-2) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CXCR2(196-212aa CYEDMGNNTANWRMLLR), different from the related mouse sequence by six amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CXCR2 Primary Antibody
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anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 316-360) antibody
CXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (pSer347) antibodyCXCR2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) antibodyCXCR2 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 7E9H12 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-40) antibodyCXCR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) antibodyCXCR2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-57) antibodyCXCR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 1-30), (N-Term) antibodyCXCR2 适用: 人 WB, IHC, FACS 宿主: 兔 Chimeric SE2 unconjugated Recombinant Antibody
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (Extracellular Domain) antibodyCXCR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibodyCXCR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (C-Term) antibodyCXCR2 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion." in: Molecular pain, Vol. 12, (2016) (PubMed).
: "NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice." in: Journal of neuroinflammation, Vol. 11, pp. 38, (2014) (PubMed).
: "Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2." in: Experimental neurology, Vol. 261, pp. 328-36, (2014) (PubMed).
: "Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice." in: Brain : a journal of neurology, Vol. 137, Issue Pt 8, pp. 2193-209, (2014) (PubMed).
: "Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons." in: Pain, Vol. 154, Issue 10, pp. 2185-97, (2013) (PubMed).
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: "Overexpression of GRK6 attenuates neuropathic pain via suppression of CXCR2 in rat dorsal root ganglion." in: Molecular pain, Vol. 12, (2016) (PubMed).
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- 抗原
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
- 别名
- CXCR2 (CXCR2 产品)
- 别名
- CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
- 背景
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CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Synonyms: C-X-C chemokine receptor type 2 antibody|CD 182 antibody|CD182 antibody|CD182 antigen antibody|CDw128b antibody|Chemokine(CXC) receptor 2 antibody|CMKAR2 antibody|CXC-R2 antibody|CXCR 2 antibody|CXCR-2 antibody|CXCR2 antibody|CXCR2_HUMAN antibody|GRO/MGSA receptor antibody|High affinity interleukin-8 receptor B antibody|IL 8 receptor type 2 antibody|IL 8R B antibody|IL-8 receptor type 2 antibody|IL-8R B antibody|IL8 RB antibody|IL8 receptor type 2 antibody|IL8R B antibody|IL8R2 antibody|IL8RA antibody|Interleukin 8 Receptor B antibody - UniProt
- P25025
- 途径
- cAMP Metabolic Process
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