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CXCR2 抗体

CXCR2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386761
发货至: 中国
  • 抗原 See all CXCR2 抗体
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    适用
    • 76
    • 37
    • 22
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 68
    • 11
    • 1
    • 1
    克隆类型
    • 70
    • 10
    • 1
    多克隆
    标记
    • 44
    • 6
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    • 2
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    • 1
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    This CXCR2 antibody is un-conjugated
    应用范围
    • 48
    • 30
    • 22
    • 19
    • 16
    • 14
    • 13
    • 8
    • 6
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CXCR2
    亚型
    IgG
    Top Product
    Discover our top product CXCR2 Primary Antibody
  • 应用备注
    WB: 1:100-1000, FCM: 1:20-100, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    别名
    Cxcr2 (CXCR2 产品)
    别名
    CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
    背景

    Synonyms: CXC-chemokine receptor 2, CD 182, CD182, CD182 antigen, CDw128b, Chemokine CXC receptor 2, CMKAR2, CXCR 2, CXC R2, CXC-R2, CXCR2_HUMAN, C-X-C chemokine receptor type 2, CXCR-2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2.

    Background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].

    基因ID
    58191
    途径
    cAMP Metabolic Process
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