CTDSP2 抗体
(CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2 (CTDSP2))
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
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Latest Publications for our CTDSP2 抗体
: "A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 26078-85, (2003) (PubMed).
Aliases for CTDSP2 抗体
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (ctdsp2) 抗体CTD small phosphatase 2 L homeolog (ctdsp2.L) 抗体
CTD small phosphatase 2 (CTDSP2) 抗体
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2) 抗体
CTD small phosphatase 2 (Ctdsp2) 抗体
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