Crossover junction endonuclease EME1 抗体
(Crossover junction endonuclease EME1 (EME1))
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:14609959}.
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22 results
Carrier-free
EME1
适用: 人
WB, IHC (p)
宿主: 小鼠
Monoclonal
MTA31 7H2-1
unconjugated
EME1
适用: 人
WB, IHC (p)
宿主: 小鼠
Monoclonal
MTA31 7H2-1
unconjugated
Latest Publications for our Crossover junction endonuclease EME1 抗体
: "The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition." in: Cancer research, Vol. 68, Issue 3, pp. 815-25, (2008) (PubMed).
: "Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3757-62, (2008) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
: "Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3757-62, (2008) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
Aliases for Crossover junction endonuclease EME1 抗体
essential meiotic structure-specific endonuclease 1 (Eme1) 抗体6820428D13 抗体
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