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COPS5 抗体

(COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: COPS5
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6815069
Recombinant COPS5 抗体 (Alexa Fluor 488) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6903511
Recombinant COPS5 抗体 (Alexa Fluor 680) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6855322
Recombinant COPS5 抗体 (Alexa Fluor 750) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6831132
Recombinant COPS5 抗体 (Alexa Fluor 594) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6887448
Recombinant COPS5 抗体 (Alexa Fluor 555) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6871385
Recombinant COPS5 抗体 (Biotin) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN7876823
COPS5 抗体 (AA 8-334) COPS5 · Primary Antibody 人, 小鼠, 大鼠 小鼠 Monoclonal 克隆位点 4G9
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • 100 μg
发货至: 中国
ABIN6871383
COPS5 抗体 (Biotin) COPS5 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6871382
COPS5 抗体 (Biotin) COPS5 · Primary Antibody 人, 小鼠 兔 Polyclonal
  • 100 μL
发货至: 中国
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 488
蛋白类型
Recombinant Antibody
产品编号 ABIN6815069
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 680
蛋白类型
Recombinant Antibody
产品编号 ABIN6903511
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 750
蛋白类型
Recombinant Antibody
产品编号 ABIN6855322
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 594
蛋白类型
Recombinant Antibody
产品编号 ABIN6831132
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 555
蛋白类型
Recombinant Antibody
产品编号 ABIN6887448
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Biotin
蛋白类型
Recombinant Antibody
产品编号 ABIN6871385
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • FACS (Flow Cytometry: 所列应用)
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆形成能力
Monoclonal
克隆
4G9
标记
unconjugated
抗体亚型
IgG2b
抗原表位
AA 8-334
产品编号 ABIN7876823
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN6871383
Primary Antibody
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN6871382

Latest Publications for our COPS5 抗体

Karpiyevich, Adjalley, Mol, Ascher, Mason, van der Heden van Noort, Laman, Ovaa, Lee, Artavanis-Tsakonas: "Nedd8 hydrolysis by UCH proteases in Plasmodium parasites." in: PLoS pathogens, Vol. 15, Issue 10, pp. e1008086, (2019) (PubMed).

Wang, Wang, Carrera, Xu, Lakshmana: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).

Wang, Dey, Carrera, Minond, Bianchi, Xu, Lakshmana: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." in: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).

Merk, Zierow, Leng, Das, Du, Schulte, Fan, Lue, Chen, Xiong, Chagnon, Bernhagen, Lolis, Mor, Lesur, Bucala: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).

Mitsuhashi, Yonemoto, Sone, Kosuge, Kosaki, Takahashi: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).

McCall, Miliani de Marval, Chastain, Jackson, He, Kotake, Cook, Xiong: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).

da Silva Correia, Miranda, Leonard, Ulevitch: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).

Burger-Kentischer, Finkelmeier, Thiele, Schmucker, Geiger, Tovar, Bernhagen: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." in: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).

Kamura, Hara, Matsumoto, Ishida, Okumura, Hatakeyama, Yoshida, Nakayama, Nakayama: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." in: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).

Yun, Tomida, Andoh, Tsuruo: "Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31296-303, (2004) (PubMed).

Aliases for COPS5 抗体

COP9 signalosome subunit 5 (CSN5) 抗体
COP9 signalosome subunit 5 (COPS5) 抗体
COP9 signalosome subunit 5 (cops5) 抗体
COP9 signalosome complex subunit 5 (CpipJ_CPIJ012314) 抗体
COP9 signalosome complex subunit 5 (Bm1_46585) 抗体
COP9 signalosome complex subunit 5 (VDBG_06932) 抗体
COP9 signalosome complex subunit 5 (LOAG_01443) 抗体
COP9 signalosome complex subunit 5 (csn5) 抗体
COP9 signalosome subunit 5 (Cops5) 抗体
COP9 signalosome subunit 5 S homeolog (cops5.S) 抗体
COP9 signalosome complex subunit 5 (csn-5) 抗体
AI303502 抗体
BcDNA.LD14392 抗体
BcDNA:LD14392 抗体
CG14884 抗体
CH5 抗体
COPS5 抗体
CSN-5 抗体
Csn5 抗体
csn5 抗体
CSN5 抗体
DCH5 抗体
Dch5 抗体
dch5 抗体
Dmel\\CG14884 抗体
JAB1 抗体
Jab1 抗体
JAB1/CSN5 抗体
jab1/csn5 抗体
JadBp 抗体
l(3)89Cf 抗体
l(3)L4032 抗体
l(3)M203 抗体
MGC76063 抗体
MOV-34 抗体
Mov34 抗体
quo 抗体
Sgn5 抗体
SGN5 抗体
zgc:73130 抗体
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