(Coatomer Protein Complex, Subunit epsilon (COPE))
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Yu, Xiong, Tenedero, Lebeau, Ni, MacDonald, Gross, Austin, Trigatti et al.: "Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol ..." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 1, pp. 26-39, (2019) (PubMed).
Styers, OConnor, Grabski, Cormet-Boyaka, Sztul: "Depletion of beta-COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1." in: American journal of physiology. Cell physiology, Vol. 294, Issue 6, pp. C1485-98, (2008) (PubMed).
Aliases for COPE 抗体
coatomer protein complex subunit epsilon (COPE) 抗体 coatomer protein complex epsilon subunit (copE) 抗体 coatomer protein complex subunit epsilon S homeolog (cope.S) 抗体 coatomer protein complex subunit epsilon (cope) 抗体 coatomer protein complex, subunit epsilon (Cope) 抗体 1110005D17Rik 抗体 COPE 抗体 Cope1 抗体 DDBDRAFT_0189670 抗体 DDBDRAFT_0233799 抗体 DDB_0189670 抗体 DDB_0233799 抗体 DKFZp469K1716 抗体 epsilon-COP 抗体 MGC80063 抗体 MGC130714 抗体