COPS5 抗体
(COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| COPS5 抗体 | 人 | 小鼠 Monoclonal |
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| COPS5 抗体 (Lys191) | 人, 小鼠 | 兔 Polyclonal |
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|
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| COPS5 抗体 (AA 1-334) | 人 | 小鼠 Polyclonal |
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|
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| COPS5 抗体 (Center) | 人, 小鼠, 大鼠, 斑马鱼, Pig, 猴 | 兔 Polyclonal |
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|
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| COPS5 抗体 (AA 374-423) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| COPS5 抗体 (N-Term) | 人, 小鼠, 大鼠, 斑马鱼, 马, 豚鼠, 兔, 犬, Cow | 兔 Polyclonal |
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| COPS5 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| COPS5 抗体 | 人, 小鼠 | 小鼠 Monoclonal |
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|
|
| COPS5 抗体 (AA 161-210) | 人, 小鼠 | 兔 Polyclonal |
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|
|
| COPS5 抗体 (AA 8-334) (Cy3) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
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| COPS5 抗体 (AA 8-334) (Cy3) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| COPS5 抗体 (AA 8-334) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| COPS5 抗体 (AA 8-334) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| COPS5 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| COPS5 抗体 (AA 8-334) (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| COPS5 抗体 (AA 8-334) (HRP) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| COPS5 抗体 (AA 8-334) (Biotin) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
|
|
|
| COPS5 抗体 (AA 8-334) (HRP) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
|
|
|
| COPS5 抗体 (AA 6-332) | 斑马鱼 | 兔 Polyclonal |
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|
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| COPS5 抗体 (AA 8-334) (APC) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Lys191
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-334
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 斑马鱼, Pig, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 374-423
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, 斑马鱼, 马, 豚鼠, 兔, 犬, Cow
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 161-210
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- Cy3
- 抗体亚型
- IgG2b
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- Biotin
- 抗体亚型
- IgG2b
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- HRP
- 抗体亚型
- IgG2b
- 抗原表位
- AA 8-334
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 6-332
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4G9
- 标记
- APC
- 抗体亚型
- IgG2b
- 抗原表位
- AA 8-334
Latest Publications for our COPS5 抗体
: "Nedd8 hydrolysis by UCH proteases in Plasmodium parasites." in: PLoS pathogens, Vol. 15, Issue 10, pp. e1008086, (2019) (PubMed).
: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).
: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." in: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).
: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).
: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).
: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).
: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).
: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." in: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).
: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." in: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).
: "Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31296-303, (2004) (PubMed).
: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).
: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." in: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).
: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).
: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).
: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." in: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).
: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).
: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." in: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).
: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." in: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).
: "Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31296-303, (2004) (PubMed).
Aliases for COPS5 抗体
COP9 signalosome subunit 5 (CSN5) 抗体COP9 signalosome subunit 5 (COPS5) 抗体
COP9 signalosome subunit 5 (cops5) 抗体
COP9 signalosome complex subunit 5 (CpipJ_CPIJ012314) 抗体
COP9 signalosome complex subunit 5 (Bm1_46585) 抗体
COP9 signalosome complex subunit 5 (VDBG_06932) 抗体
COP9 signalosome complex subunit 5 (LOAG_01443) 抗体
COP9 signalosome complex subunit 5 (csn5) 抗体
COP9 signalosome subunit 5 (Cops5) 抗体
COP9 signalosome subunit 5 S homeolog (cops5.S) 抗体
COP9 signalosome complex subunit 5 (csn-5) 抗体
AI303502 抗体
BcDNA.LD14392 抗体
BcDNA:LD14392 抗体
CG14884 抗体
CH5 抗体
COPS5 抗体
CSN-5 抗体
Csn5 抗体
csn5 抗体
CSN5 抗体
DCH5 抗体
Dch5 抗体
dch5 抗体
Dmel\\CG14884 抗体
JAB1 抗体
Jab1 抗体
JAB1/CSN5 抗体
jab1/csn5 抗体
JadBp 抗体
l(3)89Cf 抗体
l(3)L4032 抗体
l(3)M203 抗体
MGC76063 抗体
MOV-34 抗体
Mov34 抗体
quo 抗体
Sgn5 抗体
SGN5 抗体
zgc:73130 抗体
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