CLP1 抗体
(Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing\; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA- induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing (By similarity).
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CLP1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal CLP1 抗体. Click on a link to go to the corresponding products.
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Popular CLP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ICC, IF, IHC (p), WB
Validations
- (1)
- (3)
Cat. No.
ABIN2856997
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (3)
Cat. No.
ABIN564760
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (1)
Cat. No.
ABIN1537107
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN2789764
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN2789763
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN564759
Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
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Cat. No.
ABIN524369
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN524368
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Validations
Cat. No.
ABIN6389129
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
Cat. No.
ABIN1714385
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (fro), IHC (p), WB
Validations
Cat. No.
ABIN1700883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1693616
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5004394
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN5004393
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1710087
Quantity
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Datasheet
Datasheet
Latest Publications for our CLP1 抗体
: "miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage." in: Nature communications, Vol. 7, pp. 10954, (2016) (PubMed).Aliases for CLP1 抗体
cleavage and polyadenylation factor I subunit 1 (Clp1) 抗体CLP1, cleavage and polyadenylation factor I subunit (Clp1) 抗体
cyclin and CBS domain divalent metal cation transport mediator 1 (CNNM1) 抗体
cleavage and polyadenylation factor I subunit 1 (CLP1) 抗体
cleavage and polyadenylation factor I subunit 1 (clp1) 抗体
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