anti-CDKN1B (CDKN1B) 抗体产品概述

Full name:: anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) 抗体 (CDKN1B)

在www.antibodies-online.cn可供849 Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) 抗体的35不同的供货商。再加上，我们可以发CDKN1B 蛋白 (20) 和 CDKN1B 试剂盒 (16)和数多这个蛋白质的别的产品。总共936 CDKN1B产品已列进来了。

别名:: AA408329, AI843786, Cdki1b, CDKN1B, cdkn1bl, CDKN4, Kip1, MEN1B, MEN4, p27, p27Kip1, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03

列出全部抗体	基因	基因ID	UniProt
	CDKN1B	1027	P46527
	CDKN1B	83571
	CDKN1B	12576	P46414
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Human Monoclonal CDKN1B Primary Antibody for BI, IP - ABIN967391 : Gorospe, Liu, Xu, Chrest, Holbrook: Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2. in Molecular and cellular biology 1996 (PubMed)
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Mouse (Murine) Polyclonal CDKN1B Primary Antibody for DB - ABIN1881619 : Singh, Jatzek, Plisch, Srinivasan, Svaren, Suresh: Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1. in Molecular and cellular biology 2010 (PubMed)
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Human CDKN1B Primary Antibody for IHC - ABIN966733 : Eguchi, Herschenhous, Kuzushita, Moss: Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells. in Cancer research 2003 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for IHC - ABIN966734 : Le, Claret, Lammayot, Tian, Deshpande, LaPushin, Tari, Bast: The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition. in The Journal of biological chemistry 2003 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for DB - ABIN1881621 : Kajihara, Fukushige, Shioda, Tanabe, Fukunaga, Inui: CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells. in Biochemical and biophysical research communications 2010 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for DB - ABIN1881623 : Kedde, van Kouwenhove, Zwart, Oude Vrielink, Elkon, Agami: A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility. in Nature cell biology 2010 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for WB - ABIN1881620 : Canbay, Eraltan, Cercel, Isbir, Gazioglu, Aydogan, Cacina, Cengiz, Ferahman, Zengin, Unal: CCND1 and CDKN1B polymorphisms and risk of breast cancer. in Anticancer research 2010 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for DB - ABIN1881622 : Do Nascimento Borges, Burbano, Harada: Absence of CIP1/KIP1 hypermethylation in gastric cancer patients from Northern Brazil. in In vivo (Athens, Greece) 2010 (PubMed)
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Human Polyclonal CDKN1B Primary Antibody for FACS, IF (p) - ABIN672621 : Sun, Yang, Luo, Wang, Chen, Zhang, Wang, Li: Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway. in Theriogenology 2014 (PubMed)
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Human Monoclonal CDKN1B Primary Antibody for ELISA, WB - ABIN965847 : Fentress: Streams and patterns in behavior as challenges for future technologies. in Behavior research methods 2009 (PubMed)
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更多抗CDKN1B的相互作用对抗体

Human Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

FoxO3a (显示 FOXO3 抗体) overexpression increased the transcription and protein expression of Bcl2like protein 11 and cyclindependent kinase inhibitor 1B, and inhibited cyclin D1 (显示 CCND1 抗体) transcription and expression.
Results suggest that CacyBP/SIP (显示 CACYBP 抗体) plays an important role in inhibiting glioma cell migration and invasion through promoting the degradation of cytoplasmic p27 (显示 PAK2 抗体).
The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma (显示 ARHGEF16 抗体).
FLT3 (显示 FLT3 抗体) and FLT3 (显示 FLT3 抗体)-ITD can directly bind and selectively phosphorylate p27kip1 on tyrosine residue 88 in acute myeloid leukemia (显示 BCL11A 抗体). Inhibition of FLT3 (显示 FLT3 抗体)-ITD in cell lines strongly reduced p27 (显示 PAK2 抗体) tyrosine 88 phosphorylation and resulted in increased p27 (显示 PAK2 抗体) levels and cell cycle arrest
Our results suggest that oxidised photoreceptor outer segments -induced retinal pigment epithelial cell cytokinesis failure is, at least in part, due to the upregulation of p27kip1 through activating the PKC (显示 PRRT2 抗体), particularly PKCzeta (显示 PRKCZ 抗体) pathway
p27Kip1-838C>A; rs36228499 is functional in human venous smooth muscle cells (SMCs) and in adventitial cells. The AA genotype is associated with stronger expression of the p27 (显示 PAK2 抗体) gene and p27 (显示 PAK2 抗体) protein. Only the adventitial cells, and not the SMCs, are responsive to the inhibitory effects of the protective AA genotype in cell growth.
Overview of CDKN1B mutations in MEN4 (review)
Expression of CIP/KIP (显示 CIB1 抗体) proteins was found abundantly within the proliferative hair matrix, concomitant with a role in cell cycle checkpoint control. p21(CIP1 (显示 CDKN1A 抗体)), p27(KIP1) and cyclin E (显示 CCNE1 抗体) persisted within post-mitotic keratinocytes of the pre-cortex, whereas p57(KIP2 (显示 CDKN1C 抗体)) protein decreased but became nuclear.
Taken together, these data clearly show that FKBP3 (显示 FKBP3 抗体)/Sp1 (显示 PSG1 抗体)/HDAC2 (显示 HDAC2 抗体)/p27 (显示 PAK2 抗体) control cell proliferation during non-small cell lung cancer development.
Sumoylation of K73 (显示 KRT73 抗体) site of cyclin-dependent kinase inhibitor 1B (p27kip1) is critical to the nuclear-cytoplasmic translocation of p27kip1, which is mediated by RAN binding protein 2 (显示 RANBP2 抗体) and CRM1 (显示 XPO1 抗体) protein. Sumoylation of p27kip1 promotes the proliferation of cholangiocarcinoma QBC939 cells

Zebrafish Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

p27Kip1 inhibition has an effect on proliferation of bovine corneal endothelial cells by RNA interferenc

Pig (Porcine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

FoxO1a (显示 FOXO1 抗体) can regulate p27kip nuclear localization
the activation of Rac1 due to the cell-cell contact plays a critical role in the transcriptional up-regulation of p27Kip1 in vascular endothelial cells.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) interaction partners

Although expressed in all retinal cell types, p27 is required to maintain the quiescence of specific cell types including bipolar cells, Muller glia, and cones while it is dispensable for preventing cell cycle reentry in other cell types
Findings demonstrate functional interplay between a transcriptional regulator and p27(kip1) to mediate neuroprogenitor cell cycle exit, as well as to promote radial migration through a molecular mechanism consistent with suppression of RhoA (显示 RHOA 抗体) signaling.
Specifically, the proteins p18INK4C (显示 CDKN2C 抗体), p21CIP1 (显示 CDKN1A 抗体) and p27KIP1 seem to play an outstanding role in the maintenance of the differentiated state of adipocytes.
Data show that both bone marrow-derived and gastric epithelial cells contribute to the increased gastric cancer susceptibility of p27-deficient Helicobacter pylori (H. pylori) -infected mice.
Our results revealed that CKS1 (显示 CKS1B 抗体) is involved in normal glutamatergic synapse development and dendritic spine maturation in adult hippocampus through modulating p27 stability.
p27kip1 is involved in the decisive step around cell-cycle exit and plays an important role in activity-regulated and functionally relevant adult hippocampal neurogenesis.
p27(Kip1)-target genes are involved in cell adhesion and cell signaling in mouse embryonic fibroblasts.
This study demonstrates that LMP2A uses the role of MYC (显示 MYC 抗体) in the cell cycle, particularly in the p27(kip1) degradation process, to accelerate lymphomagenesis in vivo.
Study reports that p27 normally exerts a negative feedback on p21 (显示 D4S234E 抗体) expression: p27 directly represses the expression of the transcription factor Pitx2 (显示 PITX2 抗体) which in turn maintains decreased p21 (显示 D4S234E 抗体) levels. Consequently, in cells lacking p27, de-repression of Pitx2 (显示 PITX2 抗体) causes the up-regulation of p21 (显示 D4S234E 抗体) showing a new mechanism by which p27 regulates cell cycle progression by transcriptionally regulating the expression of Pitx2 (显示 PITX2 抗体) and p21 (显示 D4S234E 抗体).
Fbxo7 (显示 FBXO7 抗体)-deficient immature thymocytes failed to undergo expansion in the thymus due to a lack of Cdk6 (显示 CDK6 抗体) activity, while mature T cells showed enhanced proliferative capacity upon T-cell receptor engagement due to reduced p27 levels. These studies reveal differential cell cycle regulation by Fbxo7 (显示 FBXO7 抗体) at different stages in T-cell development.

CDKN1B 抗原简介

Antigen Summary

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Alternative names and synonyms associated with CDKN1B

cyclin dependent kinase inhibitor 1B (CDKN1B) 抗体
cyclin-dependent kinase inhibitor 1Bb (cdkn1bb) 抗体
cyclin-dependent kinase inhibitor 1B (Cdkn1b) 抗体
cyclin dependent kinase inhibitor 1B (Cdkn1b) 抗体
cyclin-dependent kinase inhibitor 1Ba (cdkn1ba) 抗体

AA408329 抗体
AI843786 抗体
Cdki1b 抗体
CDKN1B 抗体
cdkn1bl 抗体
CDKN4 抗体
Kip1 抗体
MEN1B 抗体
MEN4 抗体
p27 抗体
p27Kip1 抗体
sb:cb611 抗体
wu:fb63g10 抗体
wu:fb64g10 抗体
wu:fe18e03 抗体

Protein level used designations for CDKN1B

cyclin-dependent kinase inhibitor 1B , cyclin-dependent kinase inhibitor 1b (p27, kip1) , fb64g10 , kip1 , p27 , cyclin-dependent kinase inhibitor 1B (p27, Kip1) , cyclin-dependent kinase inhibitor p27 , p27Kip1 , Cyclin-dependent kinase inhibitor 1B (p27 Kip1) , Cyclin-dependent kinase inhibitor 1B (p27, Kip1) , cyclin-dependent kinase inhibitor p27/Kip1 , Cyclin-dependent kinase inhibitor p27 , cyclin-dependent kinase inhibitor 1b, like

GENE ID	SPECIES
1027	Homo sapiens
368329	Danio rerio
374106	Gallus gallus
697188	Macaca mulatta
100127219	Ovis aries
466947	Pan troglodytes
512613	Bos taurus
403429	Canis lupus familiaris
83571	Rattus norvegicus
397584	Sus scrofa
12576	Mus musculus
100689401	Cricetulus griseus
100729359	Cavia porcellus
493958	Felis catus
402862	Danio rerio

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