(CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1))
The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010].
Brambillasca, Altkrueger, Colombo, Friederich, Eickelmann, Mark, Borgese, Solimena: "CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells." in: The Journal of biological chemistry, Vol. 287, Issue 50, pp. 41808-19, (2012) (PubMed).
Zeggini, Weedon, Lindgren, Frayling, Elliott, Lango, Timpson, Perry, Rayner, Freathy, Barrett, Shields, Morris, Ellard, Groves, Harries, Marchini, Owen, Knight, Cardon, Walker, Hitman, Morris, Doney et al.: "Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. ..." in: Science (New York, N.Y.), Vol. 316, Issue 5829, pp. 1336-41, (2007) (PubMed).
Aliases for CDKAL1 抗体
CDK5 regulatory subunit associated protein 1 like 1 (CDKAL1) 抗体 CDK5 regulatory subunit associated protein 1-like 1 (cdkal1) 抗体 CDK5 regulatory subunit associated protein 1-like 1 S homeolog (cdkal1.S) 抗体 threonylcarbamoyladenosine tRNA methylthiotransferase (LOC587594) 抗体 CDK5 regulatory subunit associated protein 1-like 1 (Cdkal1) 抗体 1190005B03Rik 抗体 6620401C13Rik 抗体 MGC76088 抗体 MGC78779 抗体 zgc:65864 抗体