Caspase 6 抗体
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our Caspase 6 抗体
: "Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding." in: Journal of neuroscience methods, Vol. 282, pp. 20-33, (2017) (PubMed).: "Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion." in: The Journal of clinical investigation, Vol. 124, Issue 3, pp. 1173-86, (2014) (PubMed).
: "Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy." in: International journal of cancer, Vol. 134, Issue 11, pp. 2726-34, (2014) (PubMed).
: "Use of molecular biomarkers to quantify the spatial distribution of effects of anticancer drugs in solid tumors." in: Molecular cancer therapeutics, Vol. 12, Issue 4, pp. 542-52, (2013) (PubMed).
: "An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells." in: British journal of cancer, (2011) (PubMed).
: "Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13729-38, (2010) (PubMed).
: "APP binds DR6 to trigger axon pruning and neuron death via distinct caspases." in: Nature, Vol. 457, Issue 7232, pp. 981-9, (2009) (PubMed).
: "Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region." in: The Journal of investigative dermatology, Vol. 124, Issue 1, pp. 46-55, (2005) (PubMed).
: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, (2004) (PubMed).
: "Regulation of caspase-6 and FLIP by the AMPK family member ARK5." in: Oncogene, Vol. 23, Issue 42, pp. 7067-75, (2004) (PubMed).
Aliases for Caspase 6 抗体
caspase 6 L homeolog (casp6.L) 抗体caspase 6 (casp6) 抗体
caspase 6, apoptosis-related cysteine peptidase (casp6) 抗体
group XIIA secretory phospholipase A2 (CASP6) 抗体
caspase-6 (CpipJ_CPIJ017008) 抗体
caspase 6 (Casp6) 抗体
caspase 6 (CASP6) 抗体
CASP6 抗体
casp6 抗体
caspase-6 抗体
mCASP-6 抗体
mch2 抗体
Mch2 抗体
MCH2 抗体
xCaspase-6 抗体
zgc:112960 抗体
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