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Cadherin 4 抗体

(Cadherin 4 (CDH4))
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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  • 抗原: Cadherin 4 (CDH4)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7871300
Cadherin 4 抗体 (AA 175-203) CDH4 · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 400 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
Ig Fraction
抗原表位
AA 175-203
产品编号 ABIN7871300

Latest Publications for our Cadherin 4 抗体

Mills, Globa, Liu, Cowan, Mobasser, Phillips, Borgland, Bamji: "Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning." in: Nature neuroscience, Vol. 20, Issue 4, pp. 540-549, (2017) (PubMed).

Cremaschi, Oliverio, Leva, Bione, Carriero, Mazzucco, Palamidessi, Scita, Biamonti, Montecucco: "Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0130561, (2015) (PubMed).

Aschauer, Gruber, Pfaller, Limonciel, Athersuch, Cavill, Khan, Gstraunthaler, Grillari, Grillari, Hewitt, Leonard, Wilmes, Jennings: "Delineation of the key aspects in the regulation of epithelial monolayer formation." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2535-50, (2013) (PubMed).

Li, Takai, Yuge, Furukawa, Tsuno, Tsukamoto, Kong, Moriyama, Narahara: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." in: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).

Johnson, Theisen, Johnson, Wheelock: "R-cadherin influences cell motility via Rho family GTPases." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31041-9, (2004) (PubMed).

Miotto, Sabbioni, Veronese, Calin, Gullini, Liboni, Gramantieri, Bolondi, Ferrazzi, Gafà, Lanza, Negrini: "Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer." in: Cancer research, Vol. 64, Issue 22, pp. 8156-9, (2004) (PubMed).

Kitagawa, Natori, Murase, Hirano, Taketani, Suzuki: "Mutation analysis of cadherin-4 reveals amino acid residues of EC1 important for the structure and function." in: Biochemical and biophysical research communications, Vol. 271, Issue 2, pp. 358-63, (2000) (PubMed).

Tanihara, Sano, Heimark, St John, Suzuki: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).

Hutton, Christofori, Chi, Edman, Guest, Hanahan, Kelly: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).

Matsunami, Miyatani, Inoue, Copeland, Gilbert, Jenkins, Takeichi: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).

Aliases for Cadherin 4 抗体

cadherin 4 (cdh4) 抗体
cadherin 4 (Cdh4) 抗体
cadherin 4, type 1, R-cadherin (retinal) (cdh4) 抗体
cadherin 4 (CDH4) 抗体
Cadherin-4 (cdh-4) 抗体
AW120700 抗体
cad4 抗体
CAD4 抗体
cadherin-4 抗体
Cdh4l 抗体
R-Cadh 抗体
R-cadherin 抗体
rcad 抗体
Rcad 抗体
RCAD 抗体
zgc:136316 抗体
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