CACNB4 抗体
(Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CACNB4 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 458-474) | 大鼠 | 小鼠 Monoclonal |
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| CACNB4 抗体 (AA 1-217) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 1-110) | 人 | 小鼠 Monoclonal |
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| CACNB4 抗体 (Middle Region) | 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, 马 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 250-300) | 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, Pig, 小鸡, 非洲爪蟾 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 361-410) | 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 马, Pig, Bat, 猴 | 兔 Polyclonal |
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| CACNB4 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 1-520) | 人 | 小鼠 Polyclonal |
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| CACNB4 抗体 (Internal Region) | 人 | 山羊 Polyclonal |
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| CACNB4 抗体 (AA 301-400) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (AbBy Fluor® 555) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (AbBy Fluor® 488) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (Cy5.5) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (Cy3) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (Cy7) | 人 | 兔 Polyclonal |
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| CACNB4 抗体 (AA 301-400) (Cy5) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- N10-7
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 458-474
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-217
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 7E1
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 1-110
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, 马
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Middle Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-520
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 555
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 488
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5.5
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy7
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy5
- 抗体亚型
- IgG
- 抗原表位
- AA 301-400
Latest Publications for our CACNB4 抗体
: "Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 2, pp. 351-66, (2015) (PubMed).
: "Differential neuronal targeting of a new and two known calcium channel ?4 subunit splice variants correlates with their regulation of gene expression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 4, pp. 1446-61, (2014) (PubMed).
: "The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 37, pp. 12289-303, (2014) (PubMed).
: "CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-? plaques in an Alzheimer's disease mouse model." in: Journal of Alzheimer's disease : JAD, Vol. 37, Issue 2, pp. 439-51, (2013) (PubMed).
: "Up-regulation of Cav?3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 6002-13, (2012) (PubMed).
: "Regional expression and subcellular localization of the voltage-gated calcium channel ? subunits in the developing mouse brain." in: Journal of neurochemistry, Vol. 122, Issue 6, pp. 1095-107, (2012) (PubMed).
: "RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction." in: Cell, Vol. 144, Issue 2, pp. 282-95, (2011) (PubMed).
: "CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation." in: Journal of neurochemistry, Vol. 112, Issue 1, pp. 150-61, (2010) (PubMed).
: "Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5776-91, (2010) (PubMed).
: "Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals." in: Journal of cellular physiology, Vol. 225, Issue 1, pp. 276-88, (2010) (PubMed).
: "Differential neuronal targeting of a new and two known calcium channel ?4 subunit splice variants correlates with their regulation of gene expression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 4, pp. 1446-61, (2014) (PubMed).
: "The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 37, pp. 12289-303, (2014) (PubMed).
: "CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-? plaques in an Alzheimer's disease mouse model." in: Journal of Alzheimer's disease : JAD, Vol. 37, Issue 2, pp. 439-51, (2013) (PubMed).
: "Up-regulation of Cav?3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 6002-13, (2012) (PubMed).
: "Regional expression and subcellular localization of the voltage-gated calcium channel ? subunits in the developing mouse brain." in: Journal of neurochemistry, Vol. 122, Issue 6, pp. 1095-107, (2012) (PubMed).
: "RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction." in: Cell, Vol. 144, Issue 2, pp. 282-95, (2011) (PubMed).
: "CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation." in: Journal of neurochemistry, Vol. 112, Issue 1, pp. 150-61, (2010) (PubMed).
: "Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5776-91, (2010) (PubMed).
: "Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals." in: Journal of cellular physiology, Vol. 225, Issue 1, pp. 276-88, (2010) (PubMed).
Aliases for CACNB4 抗体
calcium voltage-gated channel auxiliary subunit beta 4 (CACNB4) 抗体calcium channel, voltage-dependent, beta 4 subunit (Cacnb4) 抗体
calcium voltage-gated channel auxiliary subunit beta 4 (Cacnb4) 抗体
calcium channel, voltage-dependent, beta 4 subunit (cacnb4.1) 抗体
calcium channel, voltage-dependent, beta 4 subunit (cacnb4) 抗体
calcium channel, voltage-dependent, beta 4a subunit (cacnb4a) 抗体
3110038O15Rik 抗体
CAB4 抗体
CACNB4 抗体
cacnb4.2 抗体
CACNLB4 抗体
Cchb4 抗体
EA5 抗体
EIG9 抗体
EJM 抗体
EJM4 抗体
EJM6 抗体
lethargic 抗体
lh 抗体
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