CACNB4 抗体 (AA 301-400)
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北京 101111
Quick Overview for CACNB4 抗体 (AA 301-400) (ABIN1386644)
抗原
See all CACNB4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CACNB4/L-type Ca++ CP beta 4
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亚型
- IgG
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anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (C-Term) antibody
CACNB4 适用: 人, 小鼠 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (Middle Region) antibodyCACNB4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 1-217) antibodyCACNB4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 1-110) antibodyCACNB4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E1 unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (Internal Region) antibodyVerified CACNB4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (C-Term) antibodyCACNB4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 1-520) antibodyCACNB4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 361-410) antibodyCACNB4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (AA 250-300) antibodyCACNB4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, 犬, Pig, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
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别名
- CACNB4/L-type Ca++ CP_4
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背景
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Synonyms: CAB4, CACB4_HUMAN, Cacnb4, CACNLB4, Calcium channel voltage dependent beta 4 subunit, Calcium channel voltage dependent subunit beta 4, Calcium channel voltage-dependent subunit beta 4, Dihydropyridine sensitive L type calcium channel beta 4 subunit, EA5, EIG9, EJM, EJM4, Voltage-dependent L-type calcium channel subunit beta-4.
Background: Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.
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途径
- cAMP Metabolic Process, Skeletal Muscle Fiber Development
抗原
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