BRE 蛋白
(Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).
Recommended next Filters:
18 results
custom-made
BRE
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
BRE
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
BRE
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 80 % as determined by SDS-PAGE.
ELISA, WB
Aliases for BRE 蛋白
BRISC and BRCA1 A complex member 2 (babam2) 蛋白BRISC and BRCA1 A complex member 2 (BABAM2) 蛋白
BRISC and BRCA1 A complex member 2 (Babam2) 蛋白
brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE) 蛋白
BRISC and BRCA1 A complex member 2 L homeolog (babam2.L) 蛋白
6030405P19Rik 蛋白
AI429776 蛋白
B830038C02Rik 蛋白
brcc4 蛋白
BRCC4 蛋白
brcc45 蛋白
BRCC45 蛋白
BRE 蛋白
im:7141046 蛋白
LOC100231620 蛋白
zgc:110368 蛋白
您还需要查找其他产品吗？
You are here:
