BRCA2 蛋白
(Breast Cancer 2, Early Onset (BRCA2))
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].
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8 results
BRCA2
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
BRCA2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
BRCA2
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
BRCA2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 %
Imm
Inactive
Aliases for BRCA2 蛋白
BRCA2, DNA repair associated (BRCA2) 蛋白Breast cancer 2, early onset homolog (Brca2) 蛋白
BRCA2, DNA repair associated (Brca2) 蛋白
breast cancer 2, early onset (brca2) 蛋白
breast cancer 2, early onset (LOC584780) 蛋白
BRCA2, DNA repair associated (brca2) 蛋白
breast cancer 2, early onset (Brca2) 蛋白
30169 蛋白
AI256696 蛋白
AW045498 蛋白
BcDNA:SD25109 蛋白
brca2 蛋白
BRCA2 蛋白
BRCC2 蛋白
brcc2 蛋白
BROVCA2 蛋白
brovca2 蛋白
CG13583 蛋白
CG13584 蛋白
CG30169 蛋白
dmbrca2 蛋白
Dmel\\CG30169 蛋白
FACD 蛋白
facd 蛋白
FAD 蛋白
fad 蛋白
FAD1 蛋白
fad1 蛋白
FANCB 蛋白
fancb 蛋白
FANCD 蛋白
FANCD1 蛋白
fancd1 蛋白
Fancd1 蛋白
GLM3 蛋白
PNCA2 蛋白
RAB163 蛋白
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