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BRCA1 蛋白

(Breast Cancer 1 (BRCA1))
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].

12 results :

BRCA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1346847
 
BRCA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1346845
 
BRCA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505164
 
BRCA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7504943
 
BRCA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7575209
 
BRCA1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7415059
 
BRCA1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7403681
 
BRCA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7393967
 
BRCA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % pure WB, SDS, ELISA
产品编号 ABIN2128207
 
BRCA1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3008532
 
BRCA1 宿主: 人 宿主: Baculovirus Recombinant The purified recombinant protein is greater than 95 % homogeneous and contains no detectable protease, DNase and RNase activity. in vitro, ProA, PI
产品编号 ABIN2669409
 
BRCA1 宿主: 人 宿主: Insect Cells Recombinant > 95 % SDS
产品编号 ABIN1951924
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunoprecipitation (IP)
    • In vitro Assay (in vitro)
    • Proliferation Assay (ProA)
    • Protein Interaction (PI)
  • 适用
    • Human
    • Rat
    • Mouse
  • 图像
  • 抗体来源
    • Escherichia coli (E. coli)
    • Wheat germ
    • Baculovirus
    • Insect Cells
  • 抗原表位
    • AA 1-59
    • AA 1524-1781
    • AA 1564-1863
    • AA 1579-1811
    • AA 1581-1670
    • AA 1610-1863
    • AA 19-83
  • 标记
    • His tag
    • 非结合性
    • GST tag
    • His tag,GST tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Abbexa
    • Active Motif
    • Neuromics Antibodies

Aliases for BRCA1 蛋白

BRCA1, DNA repair associated (BRCA1) 蛋白
breast cancer 1 (brca1) 蛋白
breast cancer 1, early onset (LOC755086) 蛋白
breast cancer 1, early onset (Brca1) 蛋白
BRCA1, DNA repair associated (Brca1) 蛋白
breast cancer 1, early onset (BRCA1) 蛋白
breast cancer 1 L homeolog (brca1.L) 蛋白
brca1 蛋白
BRCA1 蛋白
BRCAI 蛋白
brcai 蛋白
BRCC1 蛋白
brcc1 蛋白
BROVCA1 蛋白
IRIS 蛋白
iris 蛋白
LOC100224649 蛋白
PNCA4 蛋白
PPP1R53 蛋白
PSCP 蛋白
pscp 蛋白
RNF53 蛋白
rnf53 蛋白
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