The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Aleksunes, Yeager, Wen, Cui, Klaassen: "Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 130, Issue 2, pp. 257-68, (2012) (PubMed).
Tougou, Fukuda, Ito, Yamazaki, Fujio, Azuma: "Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals." in: Drug metabolism and pharmacokinetics, Vol. 22, Issue 2, pp. 125-8, (2007) (PubMed).
Aliases for BAAT 抗体
bile acid-CoA:amino acid N-acyltransferase (BAAT) 抗体 bile acid-CoA:amino acid N-acyltransferase (RPIC_RS10270) 抗体 Bile acid-CoA:amino acid N-acyltransferase (Bcav_2277) 抗体 Bile acid-CoA:amino acid N-acyltransferase (Rpic12D_1765) 抗体 bile acid-Coenzyme A: amino acid N-acyltransferase (Baat) 抗体 bile acid CoA:amino acid N-acyltransferase (Baat) 抗体 bile acid-CoA:amino acid N-acyltransferase (LOC481635) 抗体 bile acid-CoA:amino acid N-acyltransferase (LOC100054567) 抗体 bile acid-CoA:amino acid N-acyltransferase (LOC786798) 抗体 AI118337 抗体 AI158864 抗体 BAAT 抗体 BACAT 抗体 BAT 抗体 kan-1 抗体