BAAT 抗体 (N-Term)
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北京 101111
Quick Overview for BAAT 抗体 (N-Term) (ABIN2782317)
抗原
See all BAAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- BAAT Antibody - N-terminal region
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序列
- IQLTATPVSA LVDEPVHIRA TGLIPFQMVS FQASLEDENG DMFYSQAHYR
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against BAAT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BAAT
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45686-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 130, Issue 2, pp. 257-68, (2012) (PubMed).
: "Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals." in: Drug metabolism and pharmacokinetics, Vol. 22, Issue 2, pp. 125-8, (2007) (PubMed).
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- BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))
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别名
- BAAT
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背景
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Background Information: BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Gene Name: Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
Alternative Symbols: BAT, HCHO, BACAT, BACD1
Protein Name: Bile acid-CoA:amino acid N-acyltransferase
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分子量
- 46 kDa
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基因ID
- 570
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NCBI登录号
- NP_001692
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UniProt
- Q14032
抗原
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