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BAAT 抗体 (N-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-BAAT antibody is suitable to detect BAAT in samples from 人, 小鼠, 大鼠, 马, 兔, Cow, 犬 和 豚鼠. It has been validated for WB.
产品编号 ABIN2782317
发货至: 中国
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Quick Overview for BAAT 抗体 (N-Term) (ABIN2782317)

抗原

See all BAAT 抗体
BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

适用

人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠

宿主

  • 38
  • 3
兔

克隆类型

  • 39
  • 2
多克隆

标记

  • 16
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BAAT antibody is un-conjugated

应用范围

  • 28
  • 13
  • 13
  • 9
  • 7
  • 4
  • 3
  • 2
Western Blotting (WB)
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    N-Term

    原理

    BAAT Antibody - N-terminal region

    序列

    IQLTATPVSA LVDEPVHIRA TGLIPFQMVS FQASLEDENG DMFYSQAHYR

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against BAAT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human BAAT
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45686-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Aleksunes, Yeager, Wen, Cui, Klaassen: "Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 130, Issue 2, pp. 257-68, (2012) (PubMed).

    Tougou, Fukuda, Ito, Yamazaki, Fujio, Azuma: "Genetic polymorphism of bile acid CoA: amino acid N-acyltransferase in Japanese individuals." in: Drug metabolism and pharmacokinetics, Vol. 22, Issue 2, pp. 125-8, (2007) (PubMed).

  • 抗原

    BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

    别名

    BAAT

    背景

    Background Information: BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.

    Gene Name: Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)

    Alternative Symbols: BAT, HCHO, BACAT, BACD1

    Protein Name: Bile acid-CoA:amino acid N-acyltransferase

    分子量

    46 kDa

    基因ID

    570

    NCBI登录号

    NP_001692

    UniProt

    Q14032
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