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BAAT 抗体 (N-Term)

BAAT 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260180
发货至: 中国
  • 抗原 See all BAAT 抗体
    BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))
    抗原表位
    • 15
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 3
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This BAAT antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 13
    • 13
    • 7
    • 5
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    BAAT Antibody detects endogenous levels of total BAAT.
    预测反应
    Horse,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human BAAT, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product BAAT Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))
    别名
    BAAT (BAAT 产品)
    别名
    BACAT antibody, BAT antibody, AI118337 antibody, AI158864 antibody, kan-1 antibody, BAAT antibody, bile acid-CoA:amino acid N-acyltransferase antibody, Bile acid-CoA:amino acid N-acyltransferase antibody, bile acid-Coenzyme A: amino acid N-acyltransferase antibody, bile acid CoA:amino acid N-acyltransferase antibody, BAAT antibody, RPIC_RS10270 antibody, Bcav_2277 antibody, Rpic12D_1765 antibody, Baat antibody, LOC481635 antibody, LOC100054567 antibody, LOC786798 antibody
    背景

    Description: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

    Gene: BAAT

    分子量
    46 kDa
    基因ID
    570
    UniProt
    Q14032
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