ATRX 抗体
(helicase 2, X-linked (ATRX))
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ATRX 抗体 (Alexa Fluor 555) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (Alexa Fluor 680) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (Alexa Fluor 750) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (Alexa Fluor 647) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (Alexa Fluor 594) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (Alexa Fluor 488) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 | 人 | 小鼠 Monoclonal |
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| ATRX 抗体 | 人 | 小鼠 Monoclonal |
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| Recombinant ATRX 抗体 (full length) | 人 | 小鼠 Monoclonal |
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| Recombinant ATRX 抗体 (full length) | 人 | 小鼠 Monoclonal |
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| ATRX 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant ATRX 抗体 | 人 | 兔 Monoclonal |
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| Recombinant ATRX 抗体 | 人 | 兔 Monoclonal |
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| ATRX 抗体 | 人 | 小鼠 Monoclonal |
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| ATRX 抗体 (AA 8-289) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ATRX 抗体 | 人 | 小鼠 Monoclonal |
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| ATRX 抗体 (AA 221-270) | 人, 小鼠 | 兔 Polyclonal |
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| ATRX 抗体 (full length) | 人 | 小鼠 Monoclonal |
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| ATRX 抗体 (full length) | 人 | 小鼠 Monoclonal |
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| Recombinant ATRX 抗体 (AA 2200-2450) | 人 | 兔 Monoclonal |
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Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- rATRX-3446
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1, kappa
- 抗原表位
- full length
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- rATRX-3446
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1, kappa
- 抗原表位
- full length
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- ATMRX-1R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- ATMRX-1R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
Primary Antibody
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 8-289
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 221-270
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- ATRX-7940
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- full length
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- ATRX-7940
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- full length
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- ATRX-7188R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- AA 2200-2450
Latest Publications for our ATRX 抗体
: "Telomere elongation via alternative lengthening of telomeres (ALT) and telomerase activation in primary metastatic medulloblastoma of childhood." in: Journal of neuro-oncology, Vol. 142, Issue 3, pp. 435-444, (2019) (PubMed).
: "A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer." in: Oncology letters, Vol. 16, Issue 5, pp. 6652-6662, (2018) (PubMed).
: "Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety." in: Behavioural brain research, Vol. 311, pp. 141-6, (2016) (PubMed).
: "Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas." in: Nature communications, Vol. 6, pp. 6140, (2015) (PubMed).
: "Molecular-genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort." in: Oncotarget, Vol. 6, Issue 18, pp. 15871-81, (2015) (PubMed).
: "ATRX represses alternative lengthening of telomeres." in: Oncotarget, Vol. 6, Issue 18, pp. 16543-58, (2015) (PubMed).
: "TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast." in: British journal of cancer, Vol. 113, Issue 8, pp. 1244-8, (2015) (PubMed).
: "Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors." in: Frontiers in behavioral neuroscience, Vol. 9, pp. 313, (2015) (PubMed).
: "Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 32, Issue 8, pp. 783-90, (2014) (PubMed).
: "Clinical Neuropathology practice news 2-2014: ATRX, a new candidate biomarker in gliomas." in: Clinical neuropathology, Vol. 33, Issue 2, pp. 108-11, (2014) (PubMed).
: "A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer." in: Oncology letters, Vol. 16, Issue 5, pp. 6652-6662, (2018) (PubMed).
: "Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety." in: Behavioural brain research, Vol. 311, pp. 141-6, (2016) (PubMed).
: "Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas." in: Nature communications, Vol. 6, pp. 6140, (2015) (PubMed).
: "Molecular-genetic and clinical characteristics of gliomas with astrocytic appearance and total 1p19q loss in a single institutional consecutive cohort." in: Oncotarget, Vol. 6, Issue 18, pp. 15871-81, (2015) (PubMed).
: "ATRX represses alternative lengthening of telomeres." in: Oncotarget, Vol. 6, Issue 18, pp. 16543-58, (2015) (PubMed).
: "TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast." in: British journal of cancer, Vol. 113, Issue 8, pp. 1244-8, (2015) (PubMed).
: "Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors." in: Frontiers in behavioral neuroscience, Vol. 9, pp. 313, (2015) (PubMed).
: "Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 32, Issue 8, pp. 783-90, (2014) (PubMed).
: "Clinical Neuropathology practice news 2-2014: ATRX, a new candidate biomarker in gliomas." in: Clinical neuropathology, Vol. 33, Issue 2, pp. 108-11, (2014) (PubMed).
Aliases for ATRX 抗体
ATRX, chromatin remodeler (ATRX) 抗体ATRX, chromatin remodeler (Atrx) 抗体
alpha thalassemia/mental retardation syndrome X-linked L homeolog (atrx.L) 抗体
alpha thalassemia/mental retardation syndrome X-linked homolog (human) (atrx) 抗体
4833408C14Rik 抗体
AI447451 抗体
ATR2 抗体
atrx 抗体
atrxl 抗体
DXHXS6677E 抗体
HP1-BP38 抗体
Hp1bp2 抗体
Hp1bp38 抗体
JMS 抗体
MRXHF1 抗体
MRXS3 抗体
RAD54 抗体
Rad54 抗体
rad54 抗体
RAD54L 抗体
SFM1 抗体
SHS 抗体
wu:fb26e12 抗体
wu:fb52h08 抗体
wu:fb72g09 抗体
wu:fb94e07 抗体
XH2 抗体
XNP 抗体
Xnp 抗体
zgc:66223 抗体
ZNF-HX 抗体
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