ATRX 抗体
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北京 101111
Quick Overview for ATRX 抗体 (ABIN7880992)
抗原
See all ATRX 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- ATRX Antibody / RAD54 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant human ATRX protein was used as the immunogen for this ATRX antibody.
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亚型
- IgG1, kappa
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anti-helicase 2, X-linked (ATRX) (C-Term) antibody
ATRX 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2161-2443) antibodyATRX 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2492) antibodyATRX 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B2H9 unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2410) antibodyATRX 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-helicase 2, X-linked (ATRX) (N-Term) antibodyATRX 适用: 人, 小鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 兔 Monoclonal ATRX-2900R unconjugated Recombinant Antibody
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 小鼠 Monoclonal 39f unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 634-663), (C-Term) antibodyATRX 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20635 unconjugated
anti-helicase 2, X-linked (ATRX) (C-Term) antibodyATRX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the ATRX antibody to be titered up or down for optimal performance.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the ATRX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ATRX (helicase 2, X-linked (ATRX))
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别名
- ATRX
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背景
- ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, it contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, it predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 i± to mediate chromosomal segregation. Mutations in the gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with alpha-thalassemia or ATRX syndrome.
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UniProt
- P46100
抗原
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