ATRX 抗体 (AA 8-289)
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Quick Overview for ATRX 抗体 (AA 8-289) (ABIN7876816)
抗原
See all ATRX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-289
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原理
- ATRX Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids E8-Q289) was used as the immunogen for the ATRX antibody.
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亚型
- IgG
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anti-helicase 2, X-linked (ATRX) (C-Term) antibody
ATRX 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2161-2443) antibodyATRX 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2492) antibodyATRX 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B2H9 unconjugated
anti-helicase 2, X-linked (ATRX) (AA 2311-2410) antibodyATRX 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-helicase 2, X-linked (ATRX) (N-Term) antibodyATRX 适用: 人, 小鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 兔 Monoclonal ATRX-2900R unconjugated Recombinant Antibody
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人 IHC 宿主: 小鼠 Monoclonal 39f unconjugated
anti-helicase 2, X-linked (ATRX) antibodyATRX 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-helicase 2, X-linked (ATRX) (AA 634-663), (C-Term) antibodyATRX 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20635 unconjugated
anti-helicase 2, X-linked (ATRX) (C-Term) antibodyATRX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ATRX antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ATRX antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ATRX (helicase 2, X-linked (ATRX))
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别名
- ATRX
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背景
- Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene. It is mapped to Xq21.1. The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
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UniProt
- P46100
抗原
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