ATRX 抗体 (AA 221-270)
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北京 101111
Quick Overview for ATRX 抗体 (AA 221-270) (ABIN1450956)
抗原
See all ATRX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-270
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原理
- Rad54 Antibody
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特异性
- Rad54 Polyclonal Antibody detects endogenous levels of Rad54 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RAD54L. AA range:221-270
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATRX (helicase 2, X-linked (ATRX))
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别名
- RAD54
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背景
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Synonyms: RAD54L, RAD54A, DNA repair and recombination protein RAD54-like, RAD54 homolog, hHR54, hRAD54
Background: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008],
Gene Name: RAD54L
Protein Name: DNA repair and recombination protein RAD54-like
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分子量
- 84 kDa
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基因ID
- 8438
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OMIM
- 603615
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UniProt
- Q92698
抗原
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