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ATG4A 抗体

(Autophagy related 4A Cysteine Peptidase (ATG4A))
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2008].

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  • 抗原: ATG4A
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7880031
ATG4A 抗体 ATG4A · Primary Antibody 人 小鼠 Monoclonal 克隆位点 1458CT808-66-25-69
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 400 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
1458CT808-66-25-69
标记
unconjugated
抗体亚型
IgG2b, kappa
产品编号 ABIN7880031

Latest Publications for our ATG4A 抗体

Guo, Zhou, Gao, Zhang, Wei, Hong, Chu, Duan, Zhang, Xu: "MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells." in: PLoS ONE, Vol. 12, Issue 6, pp. e0179772, (2017) (PubMed).

Bortnik, Choutka, Horlings, Leung, Baker, Lebovitz, Dragowska, Go, Bally, Minchinton, Gelmon, Gorski: "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).

Li, Hou, Wang, Chen, Shao, Yin: "Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7327-38, (2011) (PubMed).

Lum, DeBerardinis, Thompson: "Autophagy in metazoans: cell survival in the land of plenty." in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 439-48, (2005) (PubMed).

Baehrecke: "Autophagy: dual roles in life and death?" in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 505-10, (2005) (PubMed).

Greenberg: "Degrade or die: a dual function for autophagy in the plant immune response." in: Developmental cell, Vol. 8, Issue 6, pp. 799-801, (2005) (PubMed).

Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).

Scherz-Shouval, Sagiv, Shorer, Elazar: "The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14053-8, (2003) (PubMed).

Aliases for ATG4A 抗体

autophagy related 4A cysteine peptidase L homeolog (atg4a.L) 抗体
autophagy related 4A cysteine peptidase (ATG4A) 抗体
Peptidase family C54 protein (AT2G44140) 抗体
ATG4 autophagy related 4 homolog A (S. cerevisiae) (atg4a) 抗体
autophagy related 4A, cysteine peptidase (atg4a) 抗体
autophagy related 4A, cysteine peptidase (Atg4a) 抗体
AI627006 抗体
apg4a 抗体
APG4A 抗体
Apg4a 抗体
Atg4a 抗体
Atg4al 抗体
Aut2a 抗体
autl2 抗体
AUTL2 抗体
Autl2 抗体
AV169859 抗体
F6E13.27 抗体
zgc:111958 抗体
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