ATG4A 抗体
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北京 101111
Quick Overview for ATG4A 抗体 (ABIN7880031)
抗原
See all ATG4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ATG4A Antibody
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纯化方法
- Protein G affinity
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免疫原
- Recombinant human protein was used as the immunogen for the ATG4A antibody.
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亚型
- IgG2b, kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the ATG4A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the ATG4A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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别名
- ATG4A
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背景
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
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UniProt
- Q8WYN0
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途径
- Autophagy
抗原
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